65085-80-5

Basic information

• Product Name: 1-[4-(PHENYLSULFINYL)PHENYL]-1-ETHANONE
• Synonyms: 1-[4-(PHENYLSULFINYL)PHENYL]-1-ETHANONE;1-[4-(benzenesulfinyl)phenyl]ethan-1-one
• CAS NO: 65085-80-5
• Molecular Formula: C₁₄H₁₂O₂S
• Molecular Weight: 244.31
• Mol File: 65085-80-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[4-(PHENYLSULFINYL)PHENYL]-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(PHENYLSULFINYL)PHENYL]-1-ETHANONE(65085-80-5)
• EPA Substance Registry System: 1-[4-(PHENYLSULFINYL)PHENYL]-1-ETHANONE(65085-80-5)

Safety Data

• Hazardous Substances Data: 65085-80-5(Hazardous Substances Data)

Upstream product

• 10169-55-8 1-[4-(phenylthio)phenyl]ethan-1-one 
• 2712-78-9 bis-[(trifluoroacetoxy)iodo]benzene 
• 108-98-5 thiophenol 
• 62076-10-2 (tert-butylsulfinyl)benzene 
• 99-90-1 para-bromoacetophenone 
• 85533-19-3 1-benzenesulfinyl-2-trimethylsilylethane 
• 1193-82-4 racemic methyl phenyl sulfoxide 

Downstream Products

• 54394-48-8 N-(4-(phenylsulfinyl)phenyl)acetamide 
• 102285-68-7 6-hydroxy-2--2-methyl-2H-pyran-3(6H)-one 
• 10169-55-8 1-[4-(phenylthio)phenyl]ethan-1-one 

Relevant articles and documents

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.

Aluminum(III) Chloride Promoted Oxygen Transfer: Selective Oxidation of Sulfides to Sulfoxides

An efficient selective oxidation of sulfides to sulfoxides has been developed by means of AlCl 3 -promoted oxygen transfer from phenyliodine diacetate [PhI(OAc) 2 ]. AlCl 3 proved to be the optimalLewis acid for the activation of PhI(OAc) 2. Various substituted sulfides were selectively transformed into the corresponding sulfoxides in good to excellent yields (≤99%). The high efficiency, excellent functional-group compatibility, broad substrate scope, and mild conditions render the current transformation useful for the synthesis of sulfoxides.

In situ generation of highly active bis(N-heterocyclic)carbene palladium as an efficient catalyst in direct S-arylation of methylphenyl sulfoxide and the Heck reaction: Ligand steric effects in product selectivity

The use of 1,3-bis(N-heterocyclic)carbene ligands with different alkyl wingtip groups (alkyl = methyl, isopropyl and tert-butyl) is an effective method for the palladium-catalysed direct S-arylation of methylphenyl sulfoxide and C–C coupling of various of aryl halides with alkenes. The reactions proceed in moderate to good yields. Interestingly, it is shown experimentally that, by using bulkier bidentate N-heterocyclic carbene ligands, more selective catalytic systems towards cis products in Heck coupling reactions can be achieved.