65853-51-2

Basic information

• Product Name: 2-Butanone, 1-(4-methoxyphenyl)-3,3-dimethyl-
• CAS NO: 65853-51-2
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• Mol File: 65853-51-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 1-(4-methoxyphenyl)-3,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 1-(4-methoxyphenyl)-3,3-dimethyl-(65853-51-2)
• EPA Substance Registry System: 2-Butanone, 1-(4-methoxyphenyl)-3,3-dimethyl-(65853-51-2)

Safety Data

• Hazardous Substances Data: 65853-51-2(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 351531-29-8 O-potassio-3,3-dimethyl-2-butanone 
• 66582-09-0 1-(3,3-dimethylbut-1-yn-1-yl)-4-methoxybenzene 
• 2393-23-9 4-methoxy-benzylamine 
• 17510-46-2 3,3-dimethyl-2-(trimethylsilyl)oxy-1-butene 
• 104-94-9 4-methoxy-aniline 
• 1512864-18-4 2,2'-(2,2-dimethylpropane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 
• 123-11-5 4-methoxy-benzaldehyde 
• 79958-53-5 (E)-1-(3,3-dimethylbut-1-en-1-yl)-4-methoxybenzene 
• 64723-95-1 pinacolone enolate anion 
• 29800-93-9 diethyl phosphite 

Downstream Products

• 153822-83-4 1-(4-hydroxyphenyl)-3,3-dimethylbutan-2-one oxime 
• 153822-77-6 1-(3,5-dibromo-4-hydroxyphenyl)-3,3-dimethylbutan-2-one 
• 153822-84-5 1-(3,5-dibromo-4-hydroxyphenyl)-3,3-dimethylbutan-2-one oxime 
• 53365-39-2 1-(4-methoxyphenyl)-3,3-dimethylbutan-2-amine 
• 153822-76-5 1-(4-hydroxyphenyl)-3,3-dimethylbutan-2-one 

Relevant articles and documents

Nickel-Catalyzed Cross-Coupling of Alkyl Carboxylic Acid Derivatives with Pyridinium Salts via C-N Bond Cleavage

The electrophile-electrophile cross-coupling of carboxylic acid derivatives and alkylpyridinium salts via C-N bond cleavage is developed. The method is distinguished by its simplicity and steers us through a variety of functionalized ketones in good to excellent yields. Besides acid chlorides, carboxylic acids were also employed as acylating agents, which enabled us to incorporate acid-sensitive functional groups such as MOM, BOC, and acetal. Control experiments with TEMPO revealed a radical pathway.

Transition-Metal-Free Homologative Cross-Coupling of Aldehydes and Ketones with Geminal Bis(boron) Compounds

We report a transition-metal-free coupling of aldehydes and ketones with geminal bis(boron) building blocks which provides the coupled, homologated carbonyl compound upon oxidation. This reaction not only extends an alkyl chain containing a carbonyl group, it also simultaneously introduces a new carbonyl substituent. We demonstrate that enantiopure aldehydes with an enolizable stereogenic center undergo this reaction with complete retention of stereochemistry.