65976-78-5Relevant articles and documents
Convergent total synthesis of corallocin A
Mashiko, Tomoya,Nakazato, Yuta,Katsumura, Yuta,Kasamatsu, Akihiko,Adachi, Shinya,Kamo, Shogo,Matsuzawa, Akinobu,Sugita, Kazuyuki
, p. 5127 - 5132 (2021/06/21)
The first total synthesis of corallocin A is described herein. The Suzuki coupling reaction as a key step proceeded with high stereoselectivity and in good yield. Robust transformations, including Vilsmeier-Haack formylation and Wittig reaction, allowed for effective access to corallocin A.
CHEMICAL METHOD OF PRODUCING SMTP GROUPS OR SMTP-7 AND INTERMEDIATES USED IN THE METHOD
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, (2020/05/29)
The present invention provides a compound having a dihydropyran structure, a method of producing a compound having a dihydropyran structure, a method of producing Pre-SMTP, a method of producing a group of SMTPs, and a pharmaceutical composition. The comp
Synthesis of novel resveratrol-phthalide hybrid compounds and evaluation of their inhibitory activities of nitric oxide production
Kimachi, Tetsutaro,Ogata, Tokutaro,Doe, Misae,Sakanaka, Mariko,Nishiuchi, Arisa,Aomatsu, Mio,Tanaka, Manami,Shimizu, Maki,Yoshioka, Natsuko,Kubota, Kurumi,Teraoka, Yui,Nakajima, Chikako,Takahashi, Satoru
, p. 534 - 548 (2019/08/01)
Four types of novel resveratrol-phthalide hybrid compounds were designed and synthesized systematically by Suzuki-Miyaura cross-coupling reaction. These hybrid compounds were evaluated upon an inhibitory effect of the LPS-stimulated NO production in murine macrophage cell line, RAW264.7. As a result, two of them showed stronger inhibitory activity than the original resveratrol.