66040-34-4Relevant articles and documents
Synthesis and contractile activity of substituted 1,2,3,4- tetrahydroisoquinolines
Ivanov, Iliyan,Nikolova, Stoyanka,Aladjov, Dimo,Stefanova, Iliyana,Zagorchev, Plamen
, p. 7019 - 7042 (2011/11/05)
A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydroisoquinolines was synthesized in high yields from different ketoamides. We have developed a convenient method for the synthesis of disubstituted derivatives by interaction of
Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist
Gitto, Rosaria,Barreca, Maria Letizia,De Luca, Laura,De Sarro, Giovambattista,Ferreri, Guido,Quartarone, Silvana,Russo, Emilio,Constanti, Andrew,Chimirri, Alba
, p. 197 - 200 (2007/10/03)
N-Acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives were designed and synthesized as potential noncompetitive AMPA receptor antagonists on the basis of molecular modeling studies. Sound-induced seizure testing showed that this class o