6639-40-3

Basic information

• Product Name: 1-chloro-2-[2-(2-chlorophenyl)ethyl]benzene
• Synonyms: 1-chloro-2-[2-(2-chlorophenyl)ethyl]benzene
• CAS NO: 6639-40-3
• Molecular Formula: C₁₄H₁₂Cl₂
• Molecular Weight: 251.15
• Mol File: 6639-40-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 62.0-62.5 °C(Solv: methanol (67-56-1))
• Boiling Point: 124-134 °C(Press: 0.2 Torr)
• Appearance: /
• Density: 1.214±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-chloro-2-[2-(2-chlorophenyl)ethyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-[2-(2-chlorophenyl)ethyl]benzene(6639-40-3)
• EPA Substance Registry System: 1-chloro-2-[2-(2-chlorophenyl)ethyl]benzene(6639-40-3)

Safety Data

• Hazardous Substances Data: 6639-40-3(Hazardous Substances Data)

Usage

Chemical class

Benzene and substituted derivatives

Chlorinated derivative

Contains a chlorine atom attached to the benzene ring

Structure

Contains two phenyl rings, one of which is further substituted with a chloroethyl group

Applications

Used in manufacturing of industrial and consumer products such as pesticides, insecticides, and pharmaceuticals

Intermediate

Can be used as an intermediate in the synthesis of other organic compounds

Toxicity

Has toxic and potentially harmful properties

Precautions

Proper safety measures should be taken when handling and using this compound

Upstream product

• 65276-14-4 5,5'-Di-tert.-butyl-2,2'-dichlor-diphenylethan 
• 95-49-8 2-methylchlorobenzene 
• 3034-79-5 bis(2-methylbenzoyl) peroxide 
• 56344-09-3 bis-(2-chloro-benzyl)-selenide 
• 78808-27-2 (2-chlorobenzyl)(phenyl)selenium 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 19829-43-7 Oxalsaeure-bis-(o-chlor-benzylester) 
• 201230-82-2 carbon monoxide 
• 59485-34-6 1,2-bis(2-bromophenyl)ethane 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 312624-11-6 (2-chlorobenzyl)zinc(II) chloride 
• 57239-47-1 (2-chlorophenyl)methaneselenenyl cyanide 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 65276-28-0 5-tert.-Butyl-2-chlor-benzylchlorid 

Relevant articles and documents

Method for preparing biaryl hydrocarbon compound from alcohol compound

The invention provides a method for preparing a biaryl hydrocarbon compound from an alcohol compound. The method comprises the following steps: sequentially adding the alcohol compound, sodium borohydride and iodine (the molar ratio is 1: (2-3): (0.5-1)) into a reaction tube containing acetonitrile solvent, sealing the reaction tube, heating to 100 DEG C, reacting for 10-20 hours, quenching with water after the reaction is completed, drying an organic phase with anhydrous magnesium sulfate, and carrying out rotary evaporation to remove the solvent and obtain a target product. The method has the advantages of convenience in operation, easiness in product separation, high yield, small environmental pollution and the like, is an ideal method for producing the high-energy-density hydrocarbon by utilizing oxygen-enriched biomass raw materials, and has important practical value.

Feedstocks to Pharmacophores: Cu-Catalyzed Oxidative Arylation of Inexpensive Alkylarenes Enabling Direct Access to Diarylalkanes

A Cu-catalyzed method has been identified for selective oxidative arylation of benzylic C-H bonds with arylboronic esters. The resulting 1,1-diarylalkanes are accessed directly from inexpensive alkylarenes containing primary and secondary benzylic C-H bonds, such as toluene or ethylbenzene. All catalyst components are commercially available at low cost, and the arylboronic esters are either commercially available or easily accessible from the commercially available boronic acids. The potential utility of these methods in medicinal chemistry applications is highlighted.

Straightforward synthesis of substituted dibenzyl derivatives

The C-C bond formation by homogeneous catalysis is a powerful tool in organic synthesis. The replacement of noble metal by cheaper one for already reported methodologies is of interest for an economical purpose. The attractivity of such replacement is also enhanced if a first raw transition metal is found to be active in several processes. This work demonstrates that a common nickel complex can be used for a two-step cross-coupling procedure, namely a homocoupling reaction of benzyl derivatives and a subsequent Suzuki reaction. These consecutive reactions permit the synthesis of new polyfunctionalized dibenzyl compounds.