666718-95-2

Basic information

• Product Name: Carbamic acid, [(1S)-3-cyclohexyl-1-formylpropyl]-, 1,1-dimethylethyl ester
• CAS NO: 666718-95-2
• Molecular Formula: C15H27NO3
• Molecular Weight: 269.384
• Mol File: 666718-95-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-3-cyclohexyl-1-formylpropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-3-cyclohexyl-1-formylpropyl]-, 1,1-dimethylethyl ester(666718-95-2)
• EPA Substance Registry System: Carbamic acid, [(1S)-3-cyclohexyl-1-formylpropyl]-, 1,1-dimethylethyl ester(666718-95-2)

Safety Data

• Hazardous Substances Data: 666718-95-2(Hazardous Substances Data)

Upstream product

• 107202-31-3 (S)-2-amino-4-cyclohexylbutyric acid hydrochloride 
• 107202-32-4 (S)-2-Amino-4-cyclohexyl-butan-1-ol 
• 116611-54-2 (1S-hydroxymethyl-3-phenylpropyl)carbamic acid tert-butyl ester 
• 82732-07-8 Boc-L-homophenylalanine 
• 943-73-7 D-homophenylalanine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 107202-35-7 (S)-2-(t-boc-amino)-4-cyclohexylbutan-1-ol 

Downstream Products

• 107202-60-8 ((S)-3-Cyclohexyl-1-(S)-oxiranyl-propyl)-carbamic acid tert-butyl ester 
• 107202-59-5 ((S)-3-Cyclohexyl-1-(R)-oxiranyl-propyl)-carbamic acid tert-butyl ester 
• 107202-45-9 (S)-3-(t-boc-amino)-1-cyclohexylpent-4-ene 

Relevant articles and documents

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.

The synthesis and biological activity of a series of aldehyde inhibitors of cathepsin K are reported. Exploration of the properties of the S(1) subsite with a series of alpha-amino aldehyde derivatives substituted at the P(1) position afforded compounds with cathepsin K IC(50)s between 52 microM and 15 nM.