666824-77-7

Basic information

• Product Name: 1,1,1-Propanetricarboxylic acid, 2-[4-(trifluoromethyl)phenyl]-, triethyl ester, (2S)-
• CAS NO: 666824-77-7
• Molecular Formula: C19H23F3O6
• Molecular Weight: 404.383
• Mol File: 666824-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1,1-Propanetricarboxylic acid, 2-[4-(trifluoromethyl)phenyl]-, triethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-Propanetricarboxylic acid, 2-[4-(trifluoromethyl)phenyl]-, triethyl ester, (2S)-(666824-77-7)
• EPA Substance Registry System: 1,1,1-Propanetricarboxylic acid, 2-[4-(trifluoromethyl)phenyl]-, triethyl ester, (2S)-(666824-77-7)

Safety Data

• Hazardous Substances Data: 666824-77-7(Hazardous Substances Data)

Upstream product

• 6279-86-3 methanetricarboxylic acid triethyl ester 
• 1737-26-4 (R)-1-[4-(trifluoromethyl)phenyl]ethan-1-ol 

Relevant articles and documents

Stereoselective Carbon-Carbon Bond Formation via the Mitsunobu Displacement of Chiral Secondary Benzylic Alcohols

(Matrix presented) The stereoselective displacement of a variety of chiral benzylic alcohols with triethylmethanetricarboxylate (TEMT) under Mitsunobu conditions (DEAD, PMe3) has been demonstrated to proceed in good yield (70-94%) and with a high degree of inversion. Subsequent saponification and decarboxylation of the products thus obtained provide chiral 3-aryl-3-substituted propanoic acids without racemization.