6279-86-3 Usage
Description
Triethyl methanetricarboxylate, a clear colorless to yellow liquid after melting, is an organic compound with the chemical formula C12H20O6. It is characterized by its unique structure and properties, making it a versatile compound for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Triethyl methanetricarboxylate is used as a key intermediate in the synthesis of novel inhibitors of Hsp90, a protein that plays a crucial role in cellular signaling and protein folding. These inhibitors have potential applications in the development of new therapeutic strategies for various diseases, including cancer.
Used in HIV Treatment:
In the field of HIV research and treatment, Triethyl methanetricarboxylate is utilized in the preparation of novel dihydroquinoline-3-carboxylic acids. These compounds function as HIV-1 integrase inhibitors, which are essential in preventing the integration of the viral genome into the host's DNA, thus suppressing the replication of the virus and helping in the development of antiretroviral drugs.
Used in Chemical Synthesis:
Due to its unique chemical properties, Triethyl methanetricarboxylate can also be employed as a reagent or building block in the synthesis of various other organic compounds, contributing to the advancement of chemical research and the development of new materials and products in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 6279-86-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6279-86:
(6*6)+(5*2)+(4*7)+(3*9)+(2*8)+(1*6)=123
123 % 10 = 3
So 6279-86-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O6/c1-4-14-8(11)7(9(12)15-5-2)10(13)16-6-3/h7H,4-6H2,1-3H3
6279-86-3Relevant articles and documents
Facile synthesis of aliphatic hyperbranched polyesters based on diethyl malonate and their irreversible molecular encapsulation
Santra, Santimukul,Kumar, Anil
, p. 2126 - 2127 (2004)
Synthesis of diethyl malonate based wholly aliphatic hyperbranched polyesters having suitable polar matrix for irreversible molecular encapsulation is carried out for the first time.
Iron-catalyzed, hydrogen-mediated reductive cyclization of 1,6-enynes and diynes: Evidence for bis(imino)pyridine ligand participation
Sylvester, Kevin T.,Chirik, Paul J.
supporting information; experimental part, p. 8772 - 8774 (2009/12/04)
(Chemical Equation Presented) The bis(imino)pyridine iron dinitrogen complex (iPrPDI)Fe(N2)2 catalyzes the hydrogen-mediated reductive cyclization of enynes and diynes with turnover frequencies comparable to those of established precious metal catalysts. Amino, oxygenated, and carbon-based substrates are readily cyclized to the corresponding hetero- and carbocycles with 5 mol % iron and 4 atm H2 at 23°C. Stoichiometric reactions between selected substrates and the iron compound under a N2 atmosphere established transfer dehydrogenation from an isopropyl aryl substituent to either the enyne or diyne substrate. In situ monitoring of the catalytic reaction by 1H NMR spectroscopy coupled with deuterium labeling experiments established rapid cyclization followed by turnoverlimiting hydrogenation. Copyright
NOVEL 3, 4-PROPYLENEDIOXYTHIOPHENE DERIVATIVES WITH PENDANT FUNCTIONAL GROUPS
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Page/Page column 5-6, (2010/11/24)
The present invention relates to the syntheses of 3,4-propylenedioxythiophenes of the formula (I) wherein R represents a n-valent linear or branched, optionally substituted, aliphatic C1-Cn radical and Y represents a pendant functional group. Further, methods for the preparation of the said compounds are disclosed.
