67292-69-7

Basic information

• Product Name: 3',4'-Methylenedioxyisobutyrophenone
• Synonyms: 3',4'-Methylenedioxyisobutyrophenone;1-(1,3-benzodioxol-5-yl)-2-methylpropan-1-one
• CAS NO: 67292-69-7
• Molecular Formula: C11H12O3
• Molecular Weight: 192.2112
• Mol File: 67292-69-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 311.7°Cat760mmHg
• Flash Point: 133.3°C
• Appearance: /
• Density: 1.161g/cm³
• Vapor Pressure: 0.000555mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 3',4'-Methylenedioxyisobutyrophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4'-Methylenedioxyisobutyrophenone(67292-69-7)
• EPA Substance Registry System: 3',4'-Methylenedioxyisobutyrophenone(67292-69-7)

Safety Data

• Hazardous Substances Data: 67292-69-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H12O3/c1-7(2)11(12)8-3-4-9-10(5-8)14-6-13-9/h3-5,7H,6H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 28281-49-4 3,4-methylenedioxypropiophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 25054-53-9 3,4-(methylenedioxy)benzoyl chloride 
• 120-57-0 piperonal 
• 557-93-7 2-bromoprop-1-ene 
• 5208-87-7 1'-hydroxysafrole 
• 274-09-9 Methylenedioxybenzene 
• 79-31-2 isobutyric Acid 

Relevant articles and documents

Contra-Thermodynamic Positional Isomerization of Olefins

A light-driven method for the contra-thermodynamic positional isomerization of olefins is described. In this work, stepwise PCET activation of a more substituted and more thermodynamically stable olefin substrate is mediated by an excited-state oxidant an

Conversion of Aldehydes to Branched or Linear Ketones via Regiodivergent Rhodium-Catalyzed Vinyl Bromide Reductive Coupling-Redox Isomerization Mediated by Formate

A regiodivergent catalytic method for direct conversion of aldehydes to branched or linear alkyl ketones is described. Rhodium complexes modified by PtBu2Me catalyze formate-mediated aldehyde-vinyl bromide reductive coupling-redox isomerization to form branched ketones. Use of the less strongly coordinating ligand, PPh3, promotes vinyl-to allylrhodium isomerization en route to linear ketones. This method bypasses the 3-step sequence often used to convert aldehydes to ketones involving the addition of pre-metalated reagents to Weinreb or morpholine amides.

Methylation of C(sp3)-H/C(sp2)-H bonds with methanol catalyzed by cobalt system

A highly efficient Co-based catalytic system, composed of a commercially available Co salt, a tetradentate phosphine ligand P-(CH2CH2PPh2)3(PP3), and a base (denoted as [Co]/PP3/base), is developed for the methylation of C(sp3)-H and C(sp2)-H bonds using methanol as a methylating reagent. The Co(BF4)2.6H2O/PP3/K2CO3 catalytic system showed high catalytic activity for the methylation of C-H bonds in aryl alkyl ketones, aryl acetonitriles, and indoles, with wide substrate scope and good functional group tolerance, and methylsubstituted products were obtained in good to excellent yields at 100 °C. This cheap, readily available, and highly efficient Co-based catalytic system may have promising applications in methylation reaction using methanol.