67404-70-0

Basic information

• Product Name: Cyclohexane, (2-chloroethenyl)-, (Z)-
• CAS NO: 67404-70-0
• Molecular Formula: C8H13Cl
• Molecular Weight: 144.644
• Mol File: 67404-70-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexane, (2-chloroethenyl)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexane, (2-chloroethenyl)-, (Z)-(67404-70-0)
• EPA Substance Registry System: Cyclohexane, (2-chloroethenyl)-, (Z)-(67404-70-0)

Safety Data

• Hazardous Substances Data: 67404-70-0(Hazardous Substances Data)

Upstream product

• 156-59-2 cis-1,2-Dichloroethylene 
• 156-60-5 trans-1,2-dichloroethylene 
• 28540-81-0 (E) 2-iodo-1-chloroethylene 
• 26620-11-1 (E)-2-chlorovinylthiobenzene 
• 38238-75-4 (E)-2-chloroethenyl phenyl sulfone 
• 695-12-5 vinylcyclohexane 
• 247943-54-0 2-bromo-2-chloro-1-cyclohexylethyl acetate 
• 110-82-7 cyclohexane 
• 540-59-0 1,2-Dichloroethylene 

Relevant articles and documents

Kinetically controlled E-selective catalytic olefin metathesis

A major shortcoming in olefin metathesis, a chemical process that is central to research in several branches of chemistry, is the lack of efficient methods that kinetically favor E isomers in the product distribution. Here we show that kinetically E-selective cross-metathesis reactions may be designed to generate thermodynamically disfavored alkenyl chlorides and fluorides in high yield and with exceptional stereoselectivity.With 1.0 to 5.0 mole % of a molybdenum-based catalyst, which may be delivered in the form of air- and moisture-stable paraffin pellets, reactions typically proceed to completion within 4 hours at ambient temperature. Many isomerically pure E-alkenyl chlorides, applicable to catalytic cross-coupling transformations and found in biologically active entities, thus become easily and directly accessible. Similarly, E-alkenyl fluorides can be synthesized from simpler compounds or more complex molecules.

METATHESIS CATALYSTS AND METHODS THEREOF

The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, the present disclosure provides methods for preparing alkenyl halide with regioselectivity and/or stereoselectivity. In some embodim

Reactions of Alkylmercurials with Heteroatom-Centered Acceptor Radicals

The relative reactivities of alkylmercury halides toward PhS., PhSe., or I. decrease drastically from R = tert-butyl to R = sec-alkyl to R = n-butyl, indicative that R. is formed in the rate-determining step in the attack of these radicals upon RHgCl.The alkyl radicals thus formed will enter into chain reactions in which a heteroatom-centered radical (A.) is regenerated from substrates such as RS-SR, ArSe-SeAr, ArTe-TeAr, PhSe-SO2Ar, Cl-SO2Ph; ZCH=CHA (A = Cl, I, SPh, SO2Ph); or PhCCHA (A = I, SPh, SO2Ph). β-Styrenyl (PhCH=CHA, Ph2C=CHA) and β-phenethynyl (PhCCA) systems with A = I, Br, SO2Ph also enter into chain reactions with mercury(II) salts with the ligands PhS, PhSe, PhSO2, or (EtO)2PO.The relative reactivities of a series of reagents toward t-Bu. and of PhCH=CHA, Ph2C=CHA, and PhCCA toward c-C6H11. are reported as well as the regioselectivity of t-Bu. attack observed for 1,2-disubstituted ethylenes (ZCH=CHA) with Z and A from the group Ph, Cl, Br, I, SO2Ph, SPh, Bu3Sn.Reactions of (E)- and (Z)-PhCH=CHI or MeO2CCH=CHI with t-Bu. or c-C6H11. occurred in a regioselective and stereospecific (retention) manner.Reactions of (E)- and (Z)-ClCH=CHCl occurred in a nonstereospecific manner in which the E/Z product ratio increased with the bulk of the attacking radical.A similar effect on the E/Z product ratios was observed for (Z)-MeO2CCH=CHCl.