67447-60-3

Basic information

• Product Name: chloro-(4-chloro-phenyl)-acetic acid methyl ester
• Synonyms: chloro-(4-chloro-phenyl)-acetic acid methyl ester
• CAS NO: 67447-60-3
• Molecular Weight: 219.067
• Mol File: 67447-60-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: chloro-(4-chloro-phenyl)-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: chloro-(4-chloro-phenyl)-acetic acid methyl ester(67447-60-3)
• EPA Substance Registry System: chloro-(4-chloro-phenyl)-acetic acid methyl ester(67447-60-3)

Safety Data

• Hazardous Substances Data: 67447-60-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 75188-06-6 2-chloro-2-(4-chlorophenyl)acetyl chloride 
• 7138-34-3 p-chloromandelic acid 

Relevant articles and documents

Enantioselective α-Chlorination Reactions of in Situ Generated C1 Ammonium Enolates under Base-Free Conditions

The asymmetric α-chlorination of activated aryl acetic acid esters can be carried out with high levels of enantioselectivities utilizing commercially available isothiourea catalysts under base-free conditions. The reaction, which proceeds via the in situ formation of chiral C1 ammonium enolates, is best carried out under cryogenic conditions combined with a direct trapping of the activated α-chlorinated ester derivative to prevent epimerization, thus allowing for enantioselectivities of up to e.r. 99:1.