674768-38-8

Basic information

• Product Name: (1S,4R)-sertraline-(S)-mandelate
• Synonyms: (1S,4R)-sertraline-(S)-mandelate
• CAS NO: 674768-38-8
• Molecular Weight: 458.384
• Mol File: 674768-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,4R)-sertraline-(S)-mandelate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4R)-sertraline-(S)-mandelate(674768-38-8)
• EPA Substance Registry System: (1S,4R)-sertraline-(S)-mandelate(674768-38-8)

Safety Data

• Hazardous Substances Data: 674768-38-8(Hazardous Substances Data)

Upstream product

• 17199-29-0 (S)-Mandelic acid 
• 79836-45-6 trans-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 

Downstream Products

• 91797-60-3 trans-(1S,4R)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 

Relevant articles and documents

COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS

One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.