684262-72-4

Basic information

• Product Name: 4-((2S,3R)-3-Benzyl-4-oxo-azetidin-2-yloxy)-benzoic acid benzhydryl ester
• CAS NO: 684262-72-4
• Molecular Weight: 463.533
• Mol File: 684262-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((2S,3R)-3-Benzyl-4-oxo-azetidin-2-yloxy)-benzoic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((2S,3R)-3-Benzyl-4-oxo-azetidin-2-yloxy)-benzoic acid benzhydryl ester(684262-72-4)
• EPA Substance Registry System: 4-((2S,3R)-3-Benzyl-4-oxo-azetidin-2-yloxy)-benzoic acid benzhydryl ester(684262-72-4)

Safety Data

• Hazardous Substances Data: 684262-72-4(Hazardous Substances Data)

Upstream product

• 99-96-7 4-hydroxy-benzoic acid 
• 103700-11-4 (2S,3R)-1-t-butyldimethylsilyl-3-benzyl-4-oxo-2-azetidinecarboxylic acid 
• 908093-98-1 diazodiphenylmethane 
• 100-39-0 benzyl bromide 
• 99743-35-8 diphenylmethyl 4-hydroxybenzoate 

Downstream Products

• 256410-19-2 (2S,3R)-3-Benzyl-2-[4-(4-methyl-piperazine-1-carbonyl)-phenoxy]-4-oxo-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide 
• 256410-18-1 4-[(2S,3R)-3-Benzyl-4-oxo-1-((R)-1-phenyl-ethylcarbamoyl)-azetidin-2-yloxy]-benzoic acid 

Relevant articles and documents

Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors

3-Benzylazetidine-2-one derivatives were designed and evaluated as a novel series of chymase inhibitors. Structure-activity relationship studies of 3-benzylazetidine-2-ones led to compounds 23, which exhibited 3.1nM inhibition of human chymase and enhancement of stability in human plasma (t1/2 6 h). Copyright