69206-98-0

Basic information

• Product Name: 5-chloro-2-(2,4-dichloro-phenoxy)-benzoic acid
• CAS NO: 69206-98-0
• Molecular Weight: 317.556
• Mol File: 69206-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-(2,4-dichloro-phenoxy)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(2,4-dichloro-phenoxy)-benzoic acid(69206-98-0)
• EPA Substance Registry System: 5-chloro-2-(2,4-dichloro-phenoxy)-benzoic acid(69206-98-0)

Safety Data

• Hazardous Substances Data: 69206-98-0(Hazardous Substances Data)

Upstream product

• 56966-52-0 5-Chloro-2-(2',4'-dichlorophenoxy)aniline 
• 1422364-63-3 C₁₃H₈Cl₃NO₂ 
• 120-83-2 2,4-dichlorophenol 
• 2392-48-5 2,4,4'-trichloro-2'-nitrodiphenyl ether 
• 89-61-2 2,5-dichloronitrobenzene 

Relevant articles and documents

Novel diaryl ureas with efficacy in a mouse model of malaria

Exploration of triclosan analogs has led to novel diaryl ureas with significant potency against in vitro cultures of drug-resistant and drug-sensitive strains of the human malaria parasite Plasmodium falciparum. Compound 18 demonstrated EC50 values of 37 and 55 nM versus in vitro cultured parasite strains and promising in vivo efficacy in a Plasmodium berghei antimalarial mouse model, with >50% survival at day 31 post-treatment when administered subcutaneously at 256 mg/kg. This series of compounds provides a chemical scaffold of novel architecture, as validated by cheminformatics analysis, to pursue antimalarial drug discovery efforts.