692263-11-9

Basic information

• Product Name: 3-Butenenitrile,4-(4-fluorophenyl)-(9CI)
• Synonyms: 3-Butenenitrile,4-(4-fluorophenyl)-(9CI)
• CAS NO: 692263-11-9
• Molecular Formula: C10H8FN
• Molecular Weight: 161.1756232
• Product Categories: HALIDE
• Mol File: 692263-11-9.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Butenenitrile,4-(4-fluorophenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butenenitrile,4-(4-fluorophenyl)-(9CI)(692263-11-9)
• EPA Substance Registry System: 3-Butenenitrile,4-(4-fluorophenyl)-(9CI)(692263-11-9)

Safety Data

• Hazardous Substances Data: 692263-11-9(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 463934-02-3 phosphoric acid diethyl ester 3-(4-fluorophenyl)allyl ester 
• 557-21-1 zinc(II) cyanide 
• 459-57-4 4-fluorobenzaldehyde 
• 405-99-2 para-fluorostyrene 
• 590-17-0 cyanomethyl bromide 
• 459-32-5 4-fluorocinnamic acid 
• 624-75-9 iodoacetonitrile 
• 1765-93-1 4-fluoroboronic acid 
• 109-75-1 but-3-enenitrile 

Downstream Products

• 1145987-35-4 2,5-bis(4-fluorophenyl)furan 

Relevant articles and documents

Photo-Promoted Decarboxylative Alkylation of α, β-Unsaturated Carboxylic Acids with ICH2CN for the Synthesis of β, γ-Unsaturated Nitriles

An efficient, catalyst/photocatalyst-free, and cost-effective methodology for the decarboxylative alkylation of α,β-unsaturated carboxylic acids to synthesize β,γ-unsaturated nitriles has been developed. The reaction proceeded in an environmentally benign atmosphere of blue light-emitting diode irradiation with K2CO3 and water at room temperature. The methodology worked for a wide range of substrates (22 examples) with up to 83% yield. The protocol is also compatible for gram-scale synthesis.

Synthesis method of (E)-4-aryl-3-butenonitrile compound

The invention belongs to the technical field of organic synthesis chemistry, and discloses a synthesis method of a (E)-4-aryl-3-butenonitrile compound. According to the method, under catalysis of copper iodide, a target compound is synthesized in one step

Synthetic method for diaryl furan compound

The invention relates to a synthetic method for a diaryl furan compound with a formula (6) which is described in the specification. The synthetic method has a reaction route as shown in the specification. The synthetic method comprises the following steps: S1: allowing a compound with a formula (1) and a compound with a formula (2) to react in an organic solvent in the presence of a palladium catalyst, an organic ligand, an oxidant and an acidic compound, and after completion of the reaction, carrying out post-treatment so as to obtain a compound with a formula (3); S2, allowing the compound with the formula (3) to generate a self-cyclization reaction in an organic solvent in the presence of a catalyst, and after completion of the reaction, carrying out post-treatment so as to obtain a compound with a formula (4); and S3, allowing the compound with the formula (4) and a compound with a formula (5) to react in a solvent in the presence of a palladium catalyst, an organic ligand and an acidic compound at the atmosphere of oxygen, and after completion of the reaction, carrying out post-treatment so as to obtain a compound with a formula (6). The method provided by the invention realizes creative optimization in a plurality of technical characteristics through all steps, provides a novel synthetic method and a synthetic route for preparation of the compound, and has good industrialprospects and potential application values.