69403-16-3

Basic information

• Product Name: 2-[2-(2,2-bis-ethoxycarbonyl-ethyl)-benzyl]malonic acid diethyl ester
• Synonyms: 2-[2-(2,2-bis-ethoxycarbonyl-ethyl)-benzyl]malonic acid diethyl ester
• CAS NO: 69403-16-3
• Molecular Weight: 422.475
• Mol File: 69403-16-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-[2-(2,2-bis-ethoxycarbonyl-ethyl)-benzyl]malonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(2,2-bis-ethoxycarbonyl-ethyl)-benzyl]malonic acid diethyl ester(69403-16-3)
• EPA Substance Registry System: 2-[2-(2,2-bis-ethoxycarbonyl-ethyl)-benzyl]malonic acid diethyl ester(69403-16-3)

Safety Data

• Hazardous Substances Data: 69403-16-3(Hazardous Substances Data)

Upstream product

• 91-13-4 α,α'-dibromo-o-xylene 
• 105-53-3 diethyl malonate 
• 50423-49-9 1,2-bis(iodomethyl)benzene 
• 612-12-4 o-Xylylene dichloride 

Downstream Products

• 37949-03-4 5,6,8,9-tetrahydrobenzo[7]annulen-7-one 
• 55444-18-3 3-[2-(2-ethoxycarbonyl-ethyl)-phenyl]-propionic acid ethyl ester 
• 127183-55-5 o-xylylenedi-malonic acid 
• 871876-94-7 3,3'-(1,2-phenylene)dipropionic acid 
• 129075-84-9 3-(2-ethylphenyl)propanoic acid 

Relevant articles and documents

EMM-31 MATERIALS AND PROCESSES AND USES THEREOF

The disclosure is related to EMM-31 materials, processes, and uses of the same as well as reagents used in the preparation of the EMM-31 materials, process and intermediates for preparing these reagents.

Palladium-catalyzed distannylation of ortho-quinodimethanes

An exo-diene moiety of various ortho-quinodimethanes, regardless of its transient character, was inserted into a Sn-Sn σ-bond of hexabutyldistannane in the presence of a palladium catalyst, giving α,α′-bis(tributylstannyl)-o-xylenes straightforwardly.

Mono- vs. dialkylation of carbanions. Effects of absolute and relative acidity of the conjugate carbon acids in selectivity control

The title problem was investigated in the reaction of the dibromide 1 with carbanions 2a-2g covering a range greater than 15 pK units in DMSO. It was found that the bis(monoalkylated) product 3 arises exclusively or predominantly from the carbanions 2d-2g derived from the less acidic carbon acids 7d-7g whereas the cyclic product of dialkylation 4 prevails in the reaction of the carbanions 2a-2c derived from the more acidic carbon acids 7a-7c. The alkylation selectivity thus depends critically on the absolute acidity of the carbon acid participating in the reaction. Rationale for this novel, and on basis of earlier studies unexpected finding is provided in terms of eqs. (1)-(4).