69411-67-2 Usage
Description
2-Fluoro-4-nitrobenzotrifluoride is an organic compound characterized by the presence of a fluorine atom at the 2nd position and a nitro group at the 4th position on a benzene ring, with three fluorine atoms attached to the carbon at the 1st position. This unique molecular structure endows it with specific chemical properties that make it a valuable reagent in various synthetic applications.
Uses
Used in Pharmaceutical Synthesis:
2-Fluoro-4-nitrobenzotrifluoride is used as a reagent in the synthesis of benzylamine and benzylsulfone antagonists of the urotensin receptor (UT). Its role in this application is crucial for the development of new drugs targeting UT, which can have potential therapeutic benefits in treating cardiovascular and other related conditions.
In the pharmaceutical industry, the compound's unique structure allows for the creation of novel antagonists that can selectively bind to and inhibit the urotensin receptor, thereby modulating its activity. This can lead to the discovery of new treatments for diseases where the urotensin receptor plays a significant role in their progression or symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 69411-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,4,1 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 69411-67:
(7*6)+(6*9)+(5*4)+(4*1)+(3*1)+(2*6)+(1*7)=142
142 % 10 = 2
So 69411-67-2 is a valid CAS Registry Number.
InChI:InChI=1S/C7H3F4NO2/c8-6-3-4(12(13)14)1-2-5(6)7(9,10)11/h1-3H
69411-67-2Relevant articles and documents
Deoxofluorination of (Hetero)aromatic Acids
Alekseenko, Anatoliy N.,Bugera, Maksym Ya.,Gerus, Igor I.,Kiriakov, Oleksandr,Klipkov, Anton A.,Mykhailiuk, Pavel K.,Pustovit, Yurii,Razhyk, Bohdan,Semenov, Sergey,Starova, Viktoriia S.,Tananaiko, Oksana Yu.,Tarasenko, Karen,Tolmachev, Andrei A.,Trofymchuk, Serhii,Zaporozhets, Olga A.
, p. 3110 - 3124 (2020/03/23)
Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride. The obtained products were used as starting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines - valuable building blocks for medicinal chemistry and agrochemistry.
