694533-08-9

Basic information

• Product Name: 4-(1H-INDOL-5-YL)-BENZONITRILE
• Synonyms: 4-(1H-INDOL-5-YL)-BENZONITRILE;AKOS BAR-0446
• CAS NO: 694533-08-9
• Molecular Formula: C15H10N2
• Molecular Weight: 218.25
• Mol File: 694533-08-9.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(1H-INDOL-5-YL)-BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-INDOL-5-YL)-BENZONITRILE(694533-08-9)
• EPA Substance Registry System: 4-(1H-INDOL-5-YL)-BENZONITRILE(694533-08-9)

Safety Data

• Hazardous Substances Data: 694533-08-9(Hazardous Substances Data)

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 144104-59-6 1H-indole-5-boronic acid 
• 623-00-7 4-bromobenzenecarbonitrile 
• 10075-50-0 5-bromo-1H-indole 
• 3058-39-7 4-iodobenzonitrile 
• 138373-10-1 4-cyanophenyl mesylate 
• 16066-91-4 5-iodo-1H-indole 
• 126747-14-6 4-cyanophenylboronic acid 

Relevant articles and documents

Sterically enhanced 2-iminopyridylpalladium chlorides as recyclable ppm-palladium catalyst for Suzuki–Miyaura coupling in aqueous solution

Sterically hindered 2-iminopyridine derivatives and their palladium chlorides complexes are designed and prepared, which efficiently promote the Suzuki–Miyaura coupling (SMC) reaction in aqueous solution. Besides the good to excellent yields and broad substrate scope, these catalysts can be reused for at least four new batches of the substrates. Spontaneous separation of coupling products in the aqueous reaction medium is the additional striking feature of this catalytic process. Furthermore, catalytic performance of palladium complexes bearing the azo-bridged phenyl groups was greatly influenced by the UV irradiation due to the cis/trans photoisomerization of azo unit of the catalysts. In conclusion, titled palladium complexes provide a green, sustainable, cost-effective, and convenient process to synthesize SMC products at multi-gram-scale reaction.

Cobalt-catalyzed preparation of arylindium reagents from aryl and heteroaryl bromides

A cobalt-bathophenanthroline catalyst has been developed for the direct preparation of a variety of arylindium reagents from the corresponding aryl and heteroaryl bromides in the presence of indium metal and lithium chloride. The thus-formed arylindium reagents undergo efficient palladium-catalyzed cross-coupling reactions with aryl iodides, tolerating various functional groups including hydroxy and free amino groups.

A versatile catalyst system for suzuki-miyaura cross-coupling reactions of C(sp2)-tosylates and mesylates

Figure Presented A catalyst system for the Suzuki-Miyaura cross-coupling reactions of aryl and vinyl tosylates and mesylates has been developed. This catalyst displays excellent functional group tolerance and allows the coupling of heteroarylboronic acids