697300-78-0 Usage
Description
2-Bromo-4-vinylpyridine, with the molecular formula C7H6BrN, is a pyridine derivative that incorporates a bromine atom and a vinyl group. This chemical compound is recognized for its strong electrophilic properties, which render it a valuable intermediate in the synthesis of a wide array of organic compounds, including pharmaceuticals and agrochemicals. Its reactivity and potential health hazards necessitate careful handling, but its utility in cross-coupling reactions and polymerization processes underscores its importance in organic chemistry.
Uses
Used in Pharmaceutical Synthesis:
2-Bromo-4-vinylpyridine is utilized as a key building block in the creation of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to advancements in medicinal chemistry.
Used in Agrochemical Production:
In the agrochemical industry, 2-Bromo-4-vinylpyridine serves as an essential component in the synthesis of compounds designed to protect crops and enhance agricultural productivity. Its role in formulating effective and targeted agrochemicals is vital for sustainable farming practices.
Used as a Reagent in Chemical Reactions:
2-Bromo-4-vinylpyridine's strong electrophilic nature makes it a preferred reagent in cross-coupling reactions, which are fundamental in constructing complex organic molecules. This capability extends its applications across various fields of chemistry.
Used in Polymerization Processes:
As a component in polymerization, 2-Bromo-4-vinylpyridine contributes to the formation of polymers with specific characteristics, such as enhanced stability or reactivity. Its inclusion in polymer chemistry allows for the development of materials with tailored properties for diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 697300-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,9,7,3,0 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 697300-78:
(8*6)+(7*9)+(6*7)+(5*3)+(4*0)+(3*0)+(2*7)+(1*8)=190
190 % 10 = 0
So 697300-78-0 is a valid CAS Registry Number.
697300-78-0Relevant articles and documents
Modular Photocatalytic Synthesis of α-Trialkyl-α-Tertiary Amines
Henry Blackwell,Harris, Georgia R.,Smith, Milo A.,Gaunt, Matthew J.
supporting information, p. 15946 - 15959 (2021/10/12)
Molecules displaying an α-trialkyl-α-tertiary amine motif provide access to an important and versatile area of biologically relevant chemical space but are challenging to access through existing synthetic methods. Here, we report an operationally straightforward, multicomponent protocol for the synthesis of a range of functionally and structurally diverse α-trialkyl-α-tertiary amines, which makes use of three readily available components: dialkyl ketones, benzylamines, and alkenes. The strategy relies on the of use visible-light-mediated photocatalysis with readily available Ir(III) complexes to bring about single-electron reduction of an all-alkyl ketimine species to an α-amino radical intermediate; the α-amino radical undergoes Giese-type addition with a variety of alkenes to forge the α-trialkyl-α-tertiary amine center. The mechanism of this process is believed to proceed through an overall redox neutral pathway that involves photocatalytic redox-relay of the imine, generated from the starting amine-ketone condensation, through to an imine-derived product. This is possible because the presence of a benzylic amine component in the intermediate scaffold drives a 1,5-hydrogen atom transfer step after the Giese addition to form a stable benzylic α-amino radical, which is able to close the photocatalytic cycle. These studies detail the evolution of the reaction platform, an extensive investigation of the substrate scope, and preliminary investigation of some of the mechanistic features of this distinct photocatalytic process. We believe this transformation will provide convenient access to previously unexplored α-trialkyl-α-tertiary amine scaffolds that should be of considerable interest to practitioners of synthetic and medicinal chemistry in academic and industrial institutions.
