70119-97-0

Basic information

• Product Name: 2-Pentanone, 4-[4-(1,1-dimethylheptyl)-2-(phenylmethoxy)phenyl]-
• CAS NO: 70119-97-0
• Molecular Formula: C27H38O2
• Molecular Weight: 394.598
• Mol File: 70119-97-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Pentanone, 4-[4-(1,1-dimethylheptyl)-2-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone, 4-[4-(1,1-dimethylheptyl)-2-(phenylmethoxy)phenyl]-(70119-97-0)
• EPA Substance Registry System: 2-Pentanone, 4-[4-(1,1-dimethylheptyl)-2-(phenylmethoxy)phenyl]-(70119-97-0)

Safety Data

• Hazardous Substances Data: 70119-97-0(Hazardous Substances Data)

Upstream product

• 625-33-2 3-penten-2-one 
• 70120-16-0 1-bromo-2-benzyloxy-4-(1,1-dimethylheptyl)benzene 
• 70120-12-6 2-(3-hydroxyphenyl)-2-methyloctane 
• 70120-14-8 2-(4-bromo-3-hydroxyphenyl)-2-methyloctane 
• 70120-09-1 2-(3-benzyloxyphenyl)-2-methylpropionaldehyde 
• 70120-08-0 2-<3-(benzyloxy)phenyl>-2-methylpropionitrile 
• 70120-10-4 1-(benzyloxy)-3-(1,1-dimethyl-2-heptenyl)benzene 
• 21406-61-1 pentyltriphenylphosphonium bromide 

Downstream Products

• 70120-03-5 4-<4-(1,1-dimethylheptyl)-2-hydroxyphenyl>-2-pentanol 
• 70120-01-3 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol 
• 70119-99-2 4-<4-(1,1-dimethylheptyl)-2-hydroxyphenyl>-2-pentanone 

Relevant articles and documents

A Cannabinoid Derived Prototypical Analgesic

The synthesis and analgesic testing of 3-cyclohexanol (1) are described.Prior (SAR) studies led us to conclude that the pyran ring of 9-nor-9β-hydroxyhexahydrocannabinol (HHC) was not necessary for the expression of biological activity in this series of cannabinoids.Analysis of models and the use of molecular mechanics calculations suggested that a simpler compound, such as 1, would possess the biological activity of HHC.Compound 1 was prepared in nine steps from acetonitrile (2).Biological testing in five models of pain shows that compound 1 and morphine are equally potent as analgesics and demonstrates that the pyran ring of HHC is not necessary for biological activity.Further simplification of 1 was pursued by the synthesis of 4--2-pentanol (17), but this derivative exhibits significantly reduced analgesic activity.