70227-51-9Relevant articles and documents
Christophe,D. et al.
, p. 4435 - 4438 (1978)
COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
-
Page/Page column 89; 90, (2009/03/07)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
Synthesis of 1- and 3-Amino-5-t-butyl-1H- and -3H-v-triazolopyrimidines as Hetaryne Precursors
Tielemans, Michel,Christophe, Daniel,Promel, Robert
, p. 705 - 708 (2007/10/02)
The synthesis of the title compounds 6 and 8 has first been accomplished by reaction of O-mesitylsulfonylhydroxylamine with 5-t-butyl-3H-v-triazolopyrimidine (5) whose preparation is reported in detail.However the preferred route for the synthesis