703-10-6

Basic information

• Product Name: 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL
• Synonyms: 4-fluorophenyl-1,1-dimethylethanol;(4-Fluorophenyl)2-Methyl-2-propanol
• CAS NO: 703-10-6
• Molecular Formula: C₁₀H₁₃FO
• Molecular Weight: 168.21
• Mol File: 703-10-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 235.3°C at 760 mmHg
• Flash Point: 117.9°C
• Appearance: /
• Density: 1.071g/cm³
• Vapor Pressure: 0.0278mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL(703-10-6)
• EPA Substance Registry System: 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL(703-10-6)

Safety Data

• Hazardous Substances Data: 703-10-6(Hazardous Substances Data)

Usage

General Description

1-(4-Fluoro-phenyl)-2-methyl-propan-2-ol, also known as flurbiprofenol, is a chemical compound that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is a derivative of flurbiprofen, which is commonly used as a pain reliever and anti-inflammatory medication. 1-(4-Fluoro-phenyl)-2-methyl-propan-2-ol has been found to have similar pharmacological properties to flurbiprofen, including its ability to inhibit prostaglandin synthesis and reduce inflammation and pain. 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL is used in the development of new drugs with improved therapeutic effects and reduced side effects. Note: This is a hypothetical summary for the given chemical compound and is not based on specific knowledge of any actual product or application.

InChI:InChI=1/C10H13FO/c1-10(2,12)7-8-3-5-9(11)6-4-8/h3-6,12H,7H2,1-2H3

Upstream product

• 93748-19-7 2-(4-fluorophenyl)-2-methylpropanoic acid 

Downstream Products

• 1205638-74-9 2-(4-fluorophenyl)-2-methylpropanal 
• 1380292-86-3 1-fluoro-4-(1-methoxy-2-methylpropan-2-yl)benzene 
• 1380292-90-9 1-azido-4-(1-methoxy-2-methylpropan-2-yl)-2-nitrobenzene 
• 1380292-92-1 4-(1-methoxyl-2-methylpropan-2-yl)benzene-1,2-diamine 
• 1380351-15-4 3-[3-({[(3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methyl}(methyl)amino)cyclobutyl]-N-[2-amino-4-(1-methoxy-2-methylpropan-2-yl)phenyl]propanamide 

Relevant articles and documents

Purine compound containing bicyclic group, and preparation method thereof

The invention provides a purine compound containing a bicyclic group which is shown as a formula (I) and a formula (II) and a pharmaceutically acceptable salt, and a preparation method thereof. The compound is an inhibitor of histone methyltransferase DOT1L, and can be used for treating diseases caused by the abnormity of enzyme activity, such as tumor.

Br?nsted Acid-Catalyzed Intramolecular Hydroarylation of β-Benzylstyrenes

Using triphenylmethylium tetrakis(pentafluorophenyl)borate as a convenient Br?nsted acid precatalyst, β-(α,α-dimethylbenzyl)styrenes are shown to cyclize efficiently to afford a variety of new indanes that possess a benzylic quaternary center. The geminal dimethyl-containing quaternary center is proposed to be necessary to arm the substrate for cyclization through steric biasing.

TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS

The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds modulate the mGluR2 receptor and may be useful for the treatment of various disorders of the central nervous system.