703402-21-5 Usage
General Description
Benzenemethanamine, a-methyl-4-(phenylmethoxy)-, (aR), also known as a-methyl-4-(phenylmethoxy)benzylamine, is a chemical compound with the formula C16H17NO. It is an amine compound with a methyl and a phenylmethoxy group attached to the benzene ring. This chemical is a chiral molecule, meaning it has a stereogenic center and exists in two enantiomeric forms, labeled as (aR) and (aS). It is commonly used as a building block in the synthesis of pharmaceuticals and other biologically active compounds. The (aR) form of benzenemethanamine,a-methyl-4-(phenylmethoxy)- is particularly important in medicinal chemistry due to its specific stereochemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 703402-21-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,3,4,0 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 703402-21:
(8*7)+(7*0)+(6*3)+(5*4)+(4*0)+(3*2)+(2*2)+(1*1)=105
105 % 10 = 5
So 703402-21-5 is a valid CAS Registry Number.
703402-21-5Relevant articles and documents
Enantioselective reduction of ketoxime ethers with borane-oxazaborolidines and synthesis of the key intermediate leading to (S)-rivastigmine
Pakulski, Marcin M.,Mahato, Sanjit K.,Bosiak, Mariusz J.,Krzeminski, Marek P.,Zaidlewicz, Marek
, p. 716 - 721 (2012/09/21)
The reduction of representative alkyl aryl (E)-ketoxime O-benzyl ethers with borane catalyzed by terpene oxazaborolidines, derived from (1R)-nopinone and (1R)-camphor, gave the corresponding amines with 82-99% ee. Oxazaborolidines derived from (1S)-2-carene and (1S)-3-carene were less selective. (S)-1-(3-Methoxyphenyl)ethanamine (94% ee) the key intermediate in the synthesis of (S)-rivastigmine, was obtained by the reduction of (E)-1-(3-methoxyphenyl) ethanone O-benzyl oxime with borane/oxazaborolidine generated from (S)-valinol.
