54696-05-8

Basic information

• Product Name: 4'-Benzyloxyacetophenone
• Synonyms: 1-[4-(BENZYLOXY)PHENYL]ETHANONE;4'-BENZYLOXYACETOPHENONE;4-BENZYLOXYACETOPHENONE;Ethanone, 1-[4-(phenylmethoxy)phenyl]-;4'-Benzyloxyacetophenone,98%;4''-(Benzoyloxy)-acetophenone;4'-Benzyloxyacetophenone,99%;4'-Benzyloxyacetophnone
• CAS NO: 54696-05-8
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.27
• EINECS: -0
• Product Categories: Isoquinolines ,Quinolines ,Quinaldines;CMLLYL
• Mol File: 54696-05-8.mol
• Article Data: 100

Chemical Properties

• Melting Point: 91-94 °C
• Boiling Point: 378.6 °C at 760 mmHg
• Flash Point: 172.3 °C
• Appearance: white to cream crystalline powder
• Density: 1.1 g/cm³
• Vapor Pressure: 6.21E-06mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: soluble
• BRN: 1912124
• CAS DataBase Reference: 4'-Benzyloxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Benzyloxyacetophenone(54696-05-8)
• EPA Substance Registry System: 4'-Benzyloxyacetophenone(54696-05-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 54696-05-8(Hazardous Substances Data)

Usage

Chemical Properties

white to cream crystalline powder

Preparation

Obtained by reaction of benzyl chloride with 4-hydroxyacetophenone in the presence of KOH in acetonitrile. Then, the mixture was refluxed for 3 h.

InChI:InChI=1/C15H14O2/c1-12(16)14-7-9-15(10-8-14)17-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3

Upstream product

• 100-44-7 benzyl chloride 
• 99-93-4 4-Hydroxyacetophenone 
• 100-39-0 benzyl bromide 
• 78178-57-1 3-(4-(benzyloxy)phenyl)-3-oxopropanoic acid 
• 917-64-6 methyl magnesium iodide 
• 52805-36-4 4-benzyloxybenzonitrile 
• 13031-43-1 4-acetyloxyacetophenone 
• 149683-53-4 4-(tert-butyldimethylsilyloxy)acetophenone 
• 220820-79-1 5-[2-(4-hydroxy-phenyl)-2-methyl-[1,3]dithian-4-yl]-pentanoic acid 
• 100-51-6 benzyl alcohol 
• 7601-90-3 perchloric acid 
• 946-80-5 (benzyloxy)benzene 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 

Downstream Products

• 51345-82-5 1-<4-(benzyloxy)phenyl>-3-piperidinopropan-1-one hydrochloride 
• 36438-63-8 1-(4-[benzyloxy]phenyl)ethan-1-ol 
• 194787-92-3 N-(4-benzyloxy-phenacyl)-acetamide 
• 53090-45-2 ethyl 3-[4-(benzyloxy)phenyl]-3-oxopropanoate 
• 66742-43-6 [1-(4-Benzyloxy-phenyl)-ethyl]-(3-ethoxy-propyl)-amine 
• 38110-32-6 (E)-3-(4-Benzyloxy-phenyl)-but-2-enoic acid methyl ester 
• 4254-67-5 2-bromo-1-(4-benzyloxyphenyl)-1-ethanone 
• 95556-68-6 cis-2-Methyl-3-<4-benzyloxy-phenyl>-buten-(2)-saeure-(1)-ethylester 
• 95556-68-6 trans-2-Methyl-3-<4-benzyloxy-phenyl>-buten-(2)-saeure-(1)-ethylester 
• 106281-26-9 α-(p-benzyloxyphenyl)-α-methylfurfuryl alcohol 
• 111361-00-3 (E)-1-(4-Benzyloxy-phenyl)-3-pyridin-2-yl-propenone 
• 142472-13-7 1-(4-benzyloxyphenyl)-3-phenyl-1,3-propanedione 
• 76937-64-9 1-(4-Benzyloxy-2-methoxy-phenyl)-3-(4-benzyloxy-phenyl)-propane-1,3-dione 
• 99481-22-8 2-<4-(4-benzyloxyphenyl)-3-pentenyl>-2-methyl-1,3-dioxolane 

Relevant articles and documents

Europium complex of 5-(4-dodecyloxyphenyl)2,2’-bipyridine-6’-carboxylic acid

Based on ‘1,2,4-triazine’ methodology, a new lanthanide(III) ligand, 5-(4-dodecyloxyphenyl)-2,2’-bipyridine-6’-carboxylic acid, was synthesized, and its luminescent europium(III) complex was prepared. The solubility in organic solvents for both the ligand

Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson’s Disease

Tyrosinase is involved in the synthesis of neuromelanin in the substantia nigra, which is closely correlated with the pathogenesis of Parkinson’s disease. Herein, we identified S05014 (l-Tyr, IC50 = 6.25 ± 1.43 nM; l-Dopa, IC50 = 0.6

Chromium-Salen Complex/Nitroxyl Radical Cooperative Catalysis: A Combination for Aerobic Intramolecular Dearomative Coupling of Phenols

We describe an aerobic intramolecular dearomative coupling reaction of tethered phenols using a catalytic system consisting of a chromium-salen (Cr-salen) complex combined with a nitroxyl radical. This novel catalytic system enables formation of various spirocyclic dienone products including those unable to be accessed by previously reported methods efficiently under mild reaction conditions.