70424-94-1Relevant articles and documents
A novel and reversible multifunction probe for Al3+and F? by fluorogenic and colorimetric method
Fan, Long,Liu, Kui,Yang, Zheng-yin
, (2022/03/27)
A new highly selective and sensitive probe 2-hydroxy-1-formylnaphthalene trihydroxybenzoyl hydrazone (1) was designed and synthesized for sequential detection of Al3+ and F? ions with “OFF-ON-OFF” fluorescent signals. This probe 1 displays high selectivity towards Al3+ among 17 metal cations, the resultant complex [1-Al3+] formed by the coordination of 1 with Al3+ can be recognized as a sequential probe for sensing F?. Moreover, the formation of this 1-Al3+ complex with a 1:1 stoichiometry leads to a significant fluorescence enhancement at 505 nm with high selectivity, for that 1 shows “turn-on” fluorescence response to Al3+ with negligible interferences from other various metal cations, and the resultant sequential probe 1-Al3+ complex exhibits the nearly complete quenching of emission intensity with successive addition of F?, which is only specific for F?, without being hampered by the existence of other various anions. The lowest limit of detection (LOD) values of 1 and 1-Al3+ complex for separately sensing Al3+ and F? ions are determined to be 2.55 × 10?8 M and 1.48 × 10?7 M, respectively. In addition, 1 can severe as a highly selective probe towards Al3+ and F? ions by the “naked-eye” detection, for the solution color easily changing from colorless to yellow-green with the introduction of Al3+ and further to colorless upon subsequent addition of F?.
Cannabidiol derivative, preparation method and application thereof
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Paragraph 0027; 0035; 0038; 0051-0053, (2021/07/28)
The invention discloses a cannabidiol derivative, a preparation method and application thereof, and belongs to the technical field of medicinal chemistry, wherein the cannabidiol derivative is obtained by taking cannabidiol as a main body through a synthesis means, and an anti-tumor activity determination result shows that the cannabidiol derivative prepared by the invention has an inhibition effect on lung cancer cell strains, human breast cancer cell strains, nasopharynx cancer and drug-resistant strains thereof.
Polytopic carriers for platinum ions: From digalloyl depside to tannic acid
Fogagnolo, Marco,Bergamini, Paola,Marchesi, Elena,Marvelli, Lorenza,Gambari, Roberto,Lampronti, Ilaria
, p. 12227 - 12235 (2020/07/30)
A novel dinuclear platinum(ii) complex, namely [Pt2m-GG(Me2SO-S)4] (8, GG = deprotonated methyl digallate), was easily synthesized under solvent-free conditions by grinding a solid m/p digalloyl depside with the Pt precursor [PtCO3(Me2SO-S)2]. Similarly, platinum nuclei were introduced into the galloyl chains of tannic acid (TA). In particular, three complexes A, B and C were prepared by reacting TA as a polytopic ligand with an increasing amount of [PtCO3(Me2SO-S)2]. The antiproliferative activity of complexes 8, A, B and C together with the corresponding ligands GG and TA was tested in vitro and compared with that of cisplatin on two human tumor cell lines, A2780 (ovarian cisplatin-sensitive) and A2780cis (ovarian cisplatin-resistant), and one non-tumoral cell line, HaCat. The experiments focusing on their pro-apoptotic activity indicated that the antiproliferative activity of the most active Pt(II) complexes is associated with the induction of apoptosis. This journal is