70733-25-4

Basic information

• Product Name: 3-Bromo-5-methyl-benzene-1,2-diamine
• Synonyms: 3-Bromo-5-methyl-benzene-1,2-diamine;3-Bromo-5-methylphenylene-1,2-diamine, 3-Bromo-4,5-diaminotoluene
• CAS NO: 70733-25-4
• Molecular Formula: C₇H₉BrN₂
• Molecular Weight: 201.06376
• Mol File: 70733-25-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-Bromo-5-methyl-benzene-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-methyl-benzene-1,2-diamine(70733-25-4)
• EPA Substance Registry System: 3-Bromo-5-methyl-benzene-1,2-diamine(70733-25-4)

Safety Data

• Hazardous Substances Data: 70733-25-4(Hazardous Substances Data)

Upstream product

• 827-24-7 2-bromo-4-methyl-6-nitroaniline 
• 62827-39-8 3-Bromo-5-nitro-p-toluidine 
• 89-62-3 4-methyl-2-nitroaniline 
• 40371-61-7 N-(3-bromo-4-methyl-phenyl)acetamide 
• 103-89-9 4-Methylacetanilide 
• 449790-63-0 2-bromo-4-methyl-6-nitrophenyl azide 

Downstream Products

• 40317-55-3 3,4,8-tribromo-10-methyl-acenaphtho[1,2-b]quinoxaline 
• 116222-29-8 4-Nitro-benzoic acid N'-(9-bromo-3-hydroxy-7-methyl-4-undecyl-phenazin-2-yl)-hydrazide 
• 116222-35-6 10-Bromo-8-methyl-3-(4-nitro-phenyl)-5-undecyl-1H-4-oxa-1,2,6,11-tetraaza-naphthacene 
• 70733-29-8 7-Bromo-5-methyl-4-nitrobenzo-2,1,3-thiadiazol 
• 1092500-71-4 8-bromo-6-methyl-2-(3,4,5-trimethoxy-phenyl)-quinoxaline 
• 1123738-34-0 C₂₀H₂₂N₄ 
• 1257655-43-8 C₂₁H₁₇BrN₂O₂ 

Relevant articles and documents

Synthesis of 4,4′-bisaryl-2,2′-bisbenzimidazoles as building blocks for supramolecular structures

(Chemical Equation Presented) A series of 4,4′-bisaryl-2,2′- bisbenzimidazoles has been synthesized from the corresponding 4,4′-dibromo-2,2′-bisbenzimidazoles by Negishi coupling reactions. This procedure affords highly substituted bisbenzimidazoles.

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

Substituted benzimidazoles as modulators of Ras signaling

Benzimidazole compounds that increase the rate of SOS-mediated nucleotide exchange on Ras by binding to a functionally relevant, chemically tractable pocket on the SOS protein, as part of the Ras:SOS:Ras complex.