709-06-8

Basic information

• Product Name: 6-METHOXYQUINAZOLIN-2-AMINE
• Synonyms: 6-METHOXYQUINAZOLIN-2-AMINE;2-Amino-6-methoxyquinazoline
• CAS NO: 709-06-8
• Molecular Formula: C9H9N3O
• Molecular Weight: 175.19
• Mol File: 709-06-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-METHOXYQUINAZOLIN-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXYQUINAZOLIN-2-AMINE(709-06-8)
• EPA Substance Registry System: 6-METHOXYQUINAZOLIN-2-AMINE(709-06-8)

Safety Data

• Hazardous Substances Data: 709-06-8(Hazardous Substances Data)

Upstream product

• 887581-09-1 (2-bromo-5-methoxyphenyl)methanamine 
• 50-01-1 guanidine hydrochloride 
• 139962-95-1 2-formyl-4-methoxyphenylboronic acid 

Relevant articles and documents

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids

A new method is presented for the synthesis of 2-aminoquinazolines, which is based on a Chan-Evans-Lam coupling of (2-formylphenyl)boronic acids with guanidines. Relatively mild conditions involving the use of inexpensive CuI as a catalyst and methanol as a solvent permit the application of the method to a wide range of substrates. Nonsubstituted, N-monosubstituted, and N,N-disubstituted guanidines can be used as reactants to give the corresponding 2-aminoquinazolines in moderate yields from readily available (2-formylphenyl)boronic acids.

Tetrodotoxin.

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