710272-54-1 Usage
Description
1-(2-Chloroethyl)-4-(4-nitrophenyl)piperazine, also known as CEP, is a piperazine derivative featuring a chloroethyl group and a nitrophenyl group attached to the piperazine ring. This chemical compound is recognized for its potential cytotoxic and antitumor properties, making it a promising candidate in pharmaceutical and medical research.
Uses
Used in Pharmaceutical Research:
1-(2-Chloroethyl)-4-(4-nitrophenyl)piperazine is used as a potential antitumor agent for its demonstrated cytotoxic effects on various cancer cell lines. Studies have shown that CEP can inhibit cancer cell growth, making it a valuable compound in the development of novel cancer treatments.
Used in Overcoming Multidrug Resistance:
1-(2-Chloroethyl)-4-(4-nitrophenyl)piperazine is used as a compound to potentially overcome multidrug resistance in cancer cells. This resistance is a significant challenge in cancer treatment, and CEP's ability to counteract it could lead to more effective therapies for patients with drug-resistant cancers.
Used in Anti-inflammatory and Analgesic Applications:
CEP is also being explored for its anti-inflammatory and analgesic properties, which could make it useful in the development of new medications for conditions involving inflammation and pain. Its versatility as a chemical compound positions it as a candidate for various applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 710272-54-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,0,2,7 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 710272-54:
(8*7)+(7*1)+(6*0)+(5*2)+(4*7)+(3*2)+(2*5)+(1*4)=121
121 % 10 = 1
So 710272-54-1 is a valid CAS Registry Number.
710272-54-1Relevant articles and documents
Novel aryl piperazines for alleviation of ‘andropause’ associated prostatic disorders and depression
Gupta, Sonal,Pandey, Deepti,Mandalapu, Dhanaraju,Sharma, Vikas,Shukla, Mahendra,Singh, Seema,Singh, Nidhi,Yadav, Santosh Kumar,Tanpula, Dilip Kumar,Singh, Surabhi,Maikhuri, Jagdamba P.,Shukla, Shubha,Lal, Jawahar,Siddiqi, Mohammad I.,Gupta, Gopal,Sharma, Vishnu L.
, p. 204 - 218 (2017/04/03)
A series of seventeen piperazine derivatives have been synthesized and biologically evaluated for the management of andropause-associated prostatic disorders and depression. Five compounds 16, 19, 20, 21 and 22 significantly inhibited proliferation of and
Microwave-assisted solvent-free synthesis of 3-[(4-substituted piperazin-1-yl)alkyl] imidazo[2,1-b][1,3]benzothiazol-2(3H)-ones as serotonin3 (5-HT3) receptor antagonists
Mahesh,Venkatesha Perumal,Pandi
, p. 411 - 414 (2007/10/03)
A series of novel 3-[(4-substituted piperazin-1-yl)alkyl]imidazo[2,1-b][1, 3]benzothiazol-2(3H)-ones were prepared by microwave irradiation using alumina as solid support and also by a conventional method. The compounds were characterized by spectral data and the purity was ascertained by microanalysis. The synthesized compounds were evaluated for 5-hydroxytryptamine3 antagonisms in a longitudinal muscle-myenteric plexus preparation from guinea pig ileum against the 5-hydroxytryptamine3 agonist, 2-methyl-5-hydroxytryptamine. Among the test compounds, 3-[2-(4-methylpiperazin- 1-yl)ethyl]imidazo[2,1-6][1,3]benzothiazol-2(3H)-one (3b) showed most favorable 5-hydroxytryptamine3 antagonism (pA2 6.7) in the isolated guinea pig ileum.
