7147-50-4

Basic information

• Product Name: 1,3-bis[(4-methoxyphenyl)methylideneamino]thiourea
• CAS NO: 7147-50-4
• Molecular Formula: C₁₇H₁₈N₄O₂S
• Molecular Weight: 342.422
• Mol File: 7147-50-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 492.3°Cat760mmHg
• Flash Point: 251.5°C
• Density: 1.18g/cm³
• CAS DataBase Reference: 1,3-bis[(4-methoxyphenyl)methylideneamino]thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis[(4-methoxyphenyl)methylideneamino]thiourea(7147-50-4)
• EPA Substance Registry System: 1,3-bis[(4-methoxyphenyl)methylideneamino]thiourea(7147-50-4)

Safety Data

• Hazardous Substances Data: 7147-50-4(Hazardous Substances Data)

Usage

Chemical class

Thiourea derivatives

Physical state

White crystalline solid

Usage

Intermediate in organic synthesis

Potential application

Corrosion inhibitor for metals

Biological activity

Studied for its potential as an anti-tumor agent

Structure

Two 4-methoxyphenyl groups attached to a central thiourea moiety

Research interest

Subject of various studies due to its interesting and diverse properties

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 2231-57-4 Thiocarbohydrazide 

Downstream Products

• 119023-40-4 3-{[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-amino}-2-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazono}-thiazolidin-4-one 
• 1412457-77-2 (Z)-methyl 2-[(Z)-3-((E)-(4-methoxybenzylidene)amino)-2-((E)-(4-methoxybenzylidene)hydrazono)-4-oxothiazolidin-5-ylidene]acetate 
• 347843-91-8 4-(4-methoxy-benzylideneamino)-5-(4-methoxyphenyl)-2H-1,2,4-triazole-3(4H)-thione 
• 36951-42-5 2-(2-(4-methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one 
• 119023-46-0 N¹,N⁵-di(2-p-methoxyphenyl-4-oxothiazolidine-3-yl)thiourea 

Relevant articles and documents

Synthesis and characterization of some dithiocarbohydrazones

Three bisthiocarbohydrazones had been synthesized and characterized. The structures of the three compounds were determined by elemental analysis, IR, MS, 1HNMR and 13CNMR. The crystal structure of one of the compounds was determined

Synthesis of novel triazoles, tetrazine, thiadiazoles and their biological activities

An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved. The synthesized compounds were characterized by spectroscopic and elemental analyses, and screened for their antibacterial activities against four different strains, namely E. coli, P. aeruginosa, S. aureus and B. megaterium. In particular, the compounds 5, 24 and 26h exhibited excellent antibacterial activities compared to the reference antibiotic. To get further insight about their behavior, these compounds were tested for their antioxidant activities via SOD-like activity, DPPH free radical scavenging activity, ABST and NO, which showed promising results. Furthermore, these compounds effectively promoted the cleavage of genomic DNA as well, in the absence of any external additives.

Studies on thiazolidinones. Part II. Synthesis and fungitoxicities of thiazolidinones, thiohydantoins and their derivatives derived from thiocarbohydrazide

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