716339-53-6

Basic information

• Product Name: (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-methylpiperidine-1-carboxylate
• Synonyms: (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-methylpiperidine-1-carboxylate
• CAS NO: 716339-53-6
• Molecular Weight: 387.566
• Mol File: 716339-53-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-methylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-methylpiperidine-1-carboxylate(716339-53-6)
• EPA Substance Registry System: (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-methylpiperidine-1-carboxylate(716339-53-6)

Safety Data

• Hazardous Substances Data: 716339-53-6(Hazardous Substances Data)

Upstream product

• 869725-68-8 (S)-tert-butyl 4-(4-benzyl-3-methylpiperazin-1-yl)-4-cyanopiperidine-1-carboxylate 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 511254-92-5 (2S)-1-benzyl-2-methylpiperazine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 306296-78-6 tert-butyl-4-methyl-4-[(3S)-3-methylpiperazin-1-yl]piperidine-1-carboxylate 

Relevant articles and documents

Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity

To identify a CCR5 antagonist as an HIV-1 entry inhibitor, we designed a novel series of indane derivatives based on conformational considerations. Modification on the indane ring led to the discovery of compound 22a (INCB9471) that exhibited high affinit

Piperazinylpiperidine derivatives as chemokine receptor antagonists

The present invention relates to compounds of Formula I: wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR