71785-91-6

Basic information

• Product Name: Pyridine, 1-benzoyl-1,2,3,6-tetrahydro-
• CAS NO: 71785-91-6
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Mol File: 71785-91-6.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Pyridine, 1-benzoyl-1,2,3,6-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 1-benzoyl-1,2,3,6-tetrahydro-(71785-91-6)
• EPA Substance Registry System: Pyridine, 1-benzoyl-1,2,3,6-tetrahydro-(71785-91-6)

Safety Data

• Hazardous Substances Data: 71785-91-6(Hazardous Substances Data)

Upstream product

• 694-05-3 1,2,3,6-tetrahydropyridine 
• 93-98-1 N-phenyl benzoyl amide 
• 74542-54-4 N,N-phenyl-p-toluenesulfonylbenzamide 
• 101137-69-3 tert-butyl benzoyl(phenyl)carbamate 
• 17150-61-7 N-(but-3-en-1-yl)benzamide 
• 5274-99-7 1-benzoylisonipecotic acid 
• 98-88-4 benzoyl chloride 
• 90670-03-4 N-Benzoyl-4-piperidinopiperidine 

Downstream Products

• 71785-92-7 1-benzoyl-3,4-epoxy-piperidine 

Relevant articles and documents

Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors

To identify the ligands for σ1 receptors that are potent and selective, analogues of prezamicol and trozamicol scaffolds of carbonyl-containing vesicular acetylcholine transporter (VAChT) inhibitors were explored. Of the 23 analogues synthesize

Transamidation of: N -acyl-glutarimides with amines

The development of new transamidation reactions for the synthesis of amides is an important and active area of research due to the central role of amide linkage in various fields of chemistry. Herein, we report a new method for transamidation of N-acyl-glutarimides with amines under mild, metal-free conditions that relies on amide bond twist to weaken amidic resonance. A wide range of amines and functional groups, including electrophilic substituents that would be problematic in metal-catalyzed protocols, are tolerated under the reaction conditions. Mechanistic experiments implicate the amide bond twist, thermodynamic stability of the tetrahedral intermediate and leaving group ability of glutarimide as factors controlling the reactivity of this process. The method further establishes the synthetic utility of N-acyl-glutarimides as bench-stable, twist-perpendicular, amide-based reagents in acyl-transfer reactions by a metal-free pathway. The origin of reactivity of N-acyl-glutarimides in metal-free and metal-catalyzed processes is discussed and compared.

A medium fluorous Grubbs-Hoveyda 2nd generation catalyst for phase transfer catalysis of ring closing metathesis reactions

A fluorous Grubbs-Hoveyda metathesis catalyst supported on Teflon powder, that readily moves between the solid phase (Teflon) and the liquid phase (DMF) was prepared. By modulating the hydrophobicity of the reaction medium at the end of the reaction, the supported catalyst could be recovered by simple filtration even though the catalyst existed in a homogeneous state during the reaction. In RCM reactions, the catalyst could be reused up to three times with only a slight loss in reactivity with each subsequent cycle.