722-27-0Relevant articles and documents
Direct visualization of photo-induced disulfide through oxidative coupling ofpara-aminothiophenol
He, Wei,Xia, Chang,Gao, Peng Fei,Zhou, Jun,Li, Yuan Fang,Huang, Cheng Zhi
, p. 4190 - 4193 (2021)
Chemical transformations under visible irradiation are interesting in green preparation. Herein, a photo-oxidative coupling reaction ofpara-aminothiophenol (p-ATP) dimerizing to 4-aminophenyl disulfide (APDS) rather than 4,4′-dimercaptoazobenzene (DMAB) was achieved in water by visible light irradiation, producing monodispersed organic nanoparticlesin situwith strong light scattering visualized by the dark-field microscopy (DFM) imaging technique, owing to the formation of disulfide.
Practical and efficient recyclable oxidative system for the preparation of symmetrical disulfides under aerobic conditions
Ling, Ong Chiu,Heidelberg, Thorsten,Ching, Juan Joon,Khaligh, Nader Ghaffari
, p. 281 - 294 (2020/12/13)
An efficient and practical oxidative coupling of thiols to symmetrical disulfides is developed at room temperature under aerobic conditions. The commercially available sodium methoxide solution 30 wt. % in methanol together with the air was used as a retrievable promoter system and green oxidant, respectively, for the preparation of symmetrical disulfides. The desired products were obtained in good to high yields by an economical procedure. No overoxidation of the symmetrical disulfides was observed, and various functional groups were well tolerated in the current protocol. Moreover, the new reagent reduces the generation of hazardous waste due to its high reusability. The reaction proceeded in the absence of light, and it was not inhibited by TEMPO. Also, the low yield of TEMPO-benzyl thiol adduct was detected under these conditions. Based on our experiments, a possible mechanism was proposed in the absence and presence of TEMPO.
Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library
Drozdz, Wojciech,Stefankiewicz, Artur R.,Walczak, Anna
supporting information, p. 3641 - 3645 (2021/05/29)
Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with an imine and disulfide exchange was employed to generate a new type of fully organic triply dynamic molecular assembly.