72393-99-8Relevant articles and documents
Synthesis of iodinated and radioiodinated (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(3',4'-dichlorophenyl) notropane (β-CDIT): A ligand for the dopamine transporter
Emond,Boazi,Duchene,Chalon,Besnard,Guilloteau,Frangin
, p. 757 - 772 (1997)
The synthesis of (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(3',4'-dichlorophenyl) nortropane (β-CDIT) and its radioiodinated analogues is described. Three different synthetic methods are reported for the preparation of (E)-N-[3-(tributylstannyl)-2-enyl]-2β-carbomethoxy-3β-(3', 4'-dichlorophenyl) nortropane, which was iododestannylated for the preparation of the corresponding iodinated derivative. We also report the radiolabelling of β-CDIT with 125I or 123I that could be used for in vitro and in vivo exploration of the dopamine transporter.
The synthesis of deuterium-labelled cocaine, cocaethylene and metabolites
Everhart, E. Thomas,Jacob III, Peyton,Mendelson, John,Jones, Reese T.
, p. 1265 - 1275 (2007/10/03)
We describe the syntheses of benzoylecgonine (1,1,1-2H3)methyl ester [(2H3) cocaine], (2H5)benzoylecgonine, (2H5)benzoylecgonine methyl ester [(2H5/su