724-07-2

Basic information

• Product Name: 2,1-Benzisoxazole, 5-chloro-3-(4-chlorophenyl)-
• CAS NO: 724-07-2
• Molecular Formula: C13H7Cl2NO
• Molecular Weight: 264.111
• Mol File: 724-07-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,1-Benzisoxazole, 5-chloro-3-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,1-Benzisoxazole, 5-chloro-3-(4-chlorophenyl)-(724-07-2)
• EPA Substance Registry System: 2,1-Benzisoxazole, 5-chloro-3-(4-chlorophenyl)-(724-07-2)

Safety Data

• Hazardous Substances Data: 724-07-2(Hazardous Substances Data)

Usage

Class

benzisoxazoles

Molecular structure

a benzene ring fused to an isoxazole ring with chlorine and phenyl substituents

Common uses

in the pharmaceutical industry for the synthesis of biologically active molecules

Potential applications

in drug development for conditions such as cancer, inflammation, and neurological disorders

Value

the compound's specific chemical properties and interactions make it a valuable component in the development of new therapeutic agents.

Upstream product

• 6628-86-0 5-chloro-2-nitrobenzaldehyde 
• 4596-92-3 5-chloro-2,1-benzoisoxazole 
• 106-47-8 4-chloro-aniline 
• 100-00-5 4-chlorobenzonitrile 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 7497-53-2 2,6-dichloroacridone 
• 40539-65-9 5-chloro-3-(4-chloro-phenyl)-benzo[c]isothiazole 
• 78961-59-8 5,4'-dichloro-2-methylaminobenzophenone 
• 837-58-1 2-amino-4'-chloro-5-chlorobenzophenone 
• 99833-82-6 N-<4-chloro-2-(4-chlorobenzoyl)phenyl>-N-methylchloroacetamide 
• 99833-83-7 N-<4-chloro-2-(4-chlorobenzoyl)phenyl>-N-methylphthalimidoacetate 
• 14439-61-3 4-chlorodiazepam 

Relevant articles and documents

Practical Synthesis of Benzimidazo[1,2- A[quinolines via Rh(III)-Catalyzed C-H Activation Cascade Reaction from Imidamides and Anthranils

We report a novel and practical one-pot Rh(III)-catalyzed strategy to construct benzimidazo[1,2-a]quinolines from readily available imidamides and anthranils. The cascade reaction proceeds via a C-H amination-cyclization-cyclization process in ionic liquid without any additives and possesses simple operation, moderate-to-high yield, and broad substrate scope features, which will provide the reference for the construction of biologically active fused benzimidazoles.

Catalyst-free cyclization of anthranils and cyclic amines: One-step synthesis of rutaecarpine

An efficient synthesis of a variety of quinazolinone derivatives via a direct cyclization reaction between commercially available anthranils and cyclic amines is described. The developed transformation proceeds with the merits of high step- and atom-efficiency, a broad substrate scope, and good to excellent yields, without additional catalysts, and offers a practical way for the preparation of rutaecarpine and its derivatives with structural diversity.