72587-96-3

Basic information

• Product Name: 3-benzyl-2-hydroxy-1-methylquinolin-4(1H)-one
• CAS NO: 72587-96-3
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 265.3065
• Mol File: 72587-96-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 419.9°C at 760 mmHg
• Flash Point: 207.8°C
• Density: 1.273g/cm³
• Vapor Pressure: 8.39E-08mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 3-benzyl-2-hydroxy-1-methylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-hydroxy-1-methylquinolin-4(1H)-one(72587-96-3)
• EPA Substance Registry System: 3-benzyl-2-hydroxy-1-methylquinolin-4(1H)-one(72587-96-3)

Safety Data

• Hazardous Substances Data: 72587-96-3(Hazardous Substances Data)

Upstream product

• 110216-83-6 4-amino-3-benzyl-1-methylquinolin-2(1H)-one 
• 73281-64-8 3-benzoyl-4-hydroxy-1-methylquinolin-2(1H)-one 
• 49769-78-0 2-benzyl-malonic acid dimethyl ester 
• 76154-12-6 N-[1-(2'-methylphenyl)-ethylidene]-aniline 
• 62-53-3 aniline 
• 203123-39-1 2-Phenylamino-2-o-tolyl-propionitrile 
• 1677-46-9 4-hydroxy-1-methyl-2(1H)-quinolone 
• 78859-83-3 4-Benzoyloxy-1-methyl-1,2-dihydro-chinolin-2-on 
• 110254-69-8 3-Benzyl-4-chlor-1-methyl-2(1H)-chinolon 
• 100-51-6 benzyl alcohol 
• 773837-37-9 sodium cyanide 
• 94674-88-1 3-benzyl-3-chloro-1-methylquinoline-2,4(1H,3H)-dione 

Downstream Products

• 61469-95-2 1-methyl-1H-quinoline-2,4-dione 
• 110254-69-8 3-Benzyl-4-chlor-1-methyl-2(1H)-chinolon 
• 84261-48-3 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione 
• 110216-94-9 3-Benzyl-1-methyl-4-tosyloxy-2(1H)-chinolon 
• 110229-49-7 4-Benzylamino-3-benzyl-1-methyl-2(1H)-chinolon 
• 110229-46-4 3-benzyl-1-methyl-1H-quinolin-2-one 
• 1432733-38-4 3-benzyl-1,2-dihydro-1-methyl-2-oxoquinolin-4-yl dihydrogen phosphate hydrate 
• 94674-88-1 3-benzyl-3-chloro-1-methylquinoline-2,4(1H,3H)-dione 
• 172604-63-6 3-hydroxy-1-methylquinolin-2(1H)-one 

Relevant articles and documents

Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones

3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position

Pd/C-catalyzed alkylation of heterocyclic nucleophiles with alcohols through the "borrowing hydrogen" process

The alkylation of heterocyclic compounds is important for the synthesis of various biologically active compounds. In this paper, we present the development of a Pd/C-catalyzed alkylation of heterocyclic compounds using alcohols as the alkylating agents. T

Synthesis of 4-Hydroxy-2(1H)-pyridones from Azomethines and Substituted Dialkylmalonates

The reaction of azomethines 4 with substituted dialkyl malonates 5 leads to the formation of 3-substituted 4-hydroxy-2(1H)-pyridones 6 in moderate yields. The azomethines 4 are prepared via arylaminopropionitriles 3 or in the conventional way by acid catalyzed condensation of ketones 1 with anilines 2. Chlorination of pyridones 6 with sulfuryl chloride leads to compounds 8-10.