72621-59-1

Basic information

• Product Name: N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide
• Synonyms: N-(2-Methyl-5-nitrophenylcarbamothioyl)acetamide;N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide
• CAS NO: 72621-59-1
• Molecular Formula: C₁₀H₁₁N₃O₃S
• Molecular Weight: 253.28
• Mol File: 72621-59-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.399
• Refractive Index: 1.667
• CAS DataBase Reference: N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide(72621-59-1)
• EPA Substance Registry System: N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide(72621-59-1)

Safety Data

• Hazardous Substances Data: 72621-59-1(Hazardous Substances Data)

Usage

General Description

N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide is a chemical compound that belongs to the class of acetamides, which are derivatives of acetic acid. It is composed of acetic acid, methylamine, and a nitrophenyl group. The nitrophenyl group has a nitro (NO2) functional group attached to the aromatic ring, while the thioxomethyl group contains a sulfur atom attached to a carbonyl carbon. N-[[(2-Methyl-5-nitrophenyl)amino]thioxomethyl]acetamide has potential applications in the pharmaceutical and agricultural industries due to its diverse chemical properties and structural features. Its synthesis, characterization, and functional properties are of interest for further research and development.

InChI:InChI=1/C10H11N3O3S/c1-6-3-4-8(13(15)16)5-9(6)12-10(17)11-7(2)14/h3-5H,1-2H3,(H2,11,12,14,17)

Upstream product

• 1147550-11-5 ammonium thiocyanate 
• 75-36-5 acetyl chloride 
• 99-55-8 2-methyl-5-nitroaniline 

Downstream Products

• 1048007-94-8 N-(2-methyl-5-nitrophenyl)-4-(pyridin-3-yl)thiazol-2-amine 

Relevant articles and documents

PROCESS FOR THE SYNTHESIS OF 2-AMINOTHIAZOLE COMPOUNDS AS KINASE INHIBITORS

The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula (I) which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.