72684-95-8

Basic information

• Product Name: 4-Cyano-2,6-dimethoxyphenol
• Synonyms: 4-Cyano-2,6-dimethoxyphenol;Benzonitrile, 4-hydroxy-3,5-diMethoxy-;4-hydroxy-3,5-dimethoxybenzonitrile
• CAS NO: 72684-95-8
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17266
• Mol File: 72684-95-8.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 311.9°C at 760 mmHg
• Flash Point: 142.4°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.000298mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 4-Cyano-2,6-dimethoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyano-2,6-dimethoxyphenol(72684-95-8)
• EPA Substance Registry System: 4-Cyano-2,6-dimethoxyphenol(72684-95-8)

Safety Data

• Hazardous Substances Data: 72684-95-8(Hazardous Substances Data)

Usage

Description

4-Cyano-2,6-dimethoxyphenol, also known as 4-Hydroxy-3,5-dimethoxybenzonitrile, is an organic compound characterized by its unique molecular structure featuring a cyano group, two methoxy groups, and a hydroxyl group attached to a phenol backbone. 4-Cyano-2,6-dimethoxyphenol is known for its versatile chemical properties and potential applications in various industries.

Uses

Used in Polymer Synthesis:
4-Cyano-2,6-dimethoxyphenol is used as a reactant in the switching and extension of daisy-chain dimer polymer. Its unique structure allows for the formation of novel polymers with specific properties, making it a valuable component in the development of advanced materials for various applications.
If there are additional applications in different industries, they can be listed as follows:
Used in Pharmaceutical Industry:
4-Cyano-2,6-dimethoxyphenol can be used as an intermediate in the synthesis of various pharmaceutical compounds due to its reactive functional groups. Its ability to form covalent bonds with other molecules makes it a promising candidate for the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-Cyano-2,6-dimethoxyphenol can be employed as a building block for the creation of a wide range of organic compounds. Its versatility in reacting with various reagents opens up possibilities for the synthesis of novel molecules with potential applications in different industries, such as agriculture, materials science, and environmental science.
Used in Dye and Pigment Industry:
The unique structure of 4-Cyano-2,6-dimethoxyphenol may also find applications in the dye and pigment industry. Its ability to form stable complexes with other molecules can lead to the development of new dyes and pigments with improved color properties and stability.

InChI:InChI=1/C9H9NO3/c1-12-7-3-6(5-10)4-8(13-2)9(7)11/h3-4,11H,1-2H3

Upstream product

• 54738-29-3 4-acetoxy-3,5-dimethoxy-benzonitrile 
• 19179-31-8 3,5-dimethoxy-benzonitrile 
• 134-96-3 syringic aldehyde 
• 1885-35-4 3,4,5-trimethoxybenzonitrile 
• 2973-77-5 3,5-dibromo-4-hydroxybenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 95065-45-5 4-carbamimidoyl-2,6-dimethoxyphenol 
• 95065-30-8 Benzoic acid 4-carbamimidoyl-2,6-dimethoxy-phenyl ester 
• 1188547-68-3 C₂₀H₂₉NO₅ 
• 1239861-00-7 4-(2-chloroquinazolin-4-yloxy)-3,5-dimethoxybenzonitrile 
• 1188547-52-5 C₂₀H₃₃NO₅ 
• 1188547-50-3 C₅₈H₇₉NO₁₂ 
• 1188547-53-6 C₅₈H₈₁NO₁₂ 
• 1188547-54-7 C₅₃H₇₃NO₁₁*ClH 
• 1319736-48-5 3,5-dimethoxy-4-(4-tetrahydropyranyloxy)benzonitrile 
• 1319736-47-4 3,5-dimethoxy-4-(2-morpholine-4-yl-ethoxy)benzonitrile 
• 1357621-15-8 N,N-bis[2-(4-cyano-2,6-dimethoxyphenoxy)ethyl]benzenesulfonamide 
• 1357621-03-4 1,5-bis(4-cyano-2,6-dimethoxyphenoxy)-N-methyl-3-azapentane 

Relevant articles and documents

SMALL MOLECULE NEUTRAL SPHINGOMYELINASE 2 (NSMASE2) INHIBITORS

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Utility of Nitrogen Extrusion of Azido Complexes for the Synthesis of Nitriles, Benzoxazoles, and Benzisoxazoles

The utility of the nitrogen extrusion reaction of azido complexes, generated in situ from the corresponding aldehydes or ketones with TMSN3 in the presence of ZrCl4 or TfOH, has been described. These azido complexes could undergo three different pathways, depending on the substrates. First, azido methanolate complexes or imine diazonium ions could lead to benzisoxazole products via an intramolecular nucleophilic substitution. Second, imine diazonium ions could also undergo either the elimination of proton to provide nitrile products in good to excellent yields or an aryl migration, followed by an intramolecular nucleophilic addition, to give benzoxazole products in good yields.

SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS MEDICAMENTS

The invention relates to new substituted naphthyridines of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among —O—R3 or —NR3R4,R3 is C1-6-alkyl which is substituted by R5 and R6,R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, —C1-6-alkylen-O—C1-3-alkyl, C1-3-haloalkyl,R6 is ring X wherein n is either 0 or 1, and is a either a single or a double bond andwherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C1-3-alkyl, —C1-3-haloalkyl, —O—C1-3-alkyl, —C1-3-alkanol and halogen,and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.