727-74-2

Basic information

• Product Name: 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID
• Synonyms: 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID
• CAS NO: 727-74-2
• Molecular Formula: C14H12FNO2
• Molecular Weight: 245.25
• Mol File: 727-74-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID(727-74-2)
• EPA Substance Registry System: 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID(727-74-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 727-74-2(Hazardous Substances Data)

Upstream product

• 443-69-6 5-fluoro-1H-indole-2,3-dione 
• 108-94-1 cyclohexanone 
• 351-09-7 N-(4-fluorophenyl)-2-(hydroxyimino) acetamide 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors

A series of novel fused heterocycle methyl esters were designed and synthesized as human nonpancreatic secretory phospholipase A2 (hnps-PLA2) competitive inhibitors. Among the 22 synthesized compounds, 17 quinoline-4-methyl esters displayed hnps-PLA2 inhibition activity in the in vitro bioassay. The IC50 value for the best compound 3o was 1.5 μM. The structure-inhibition-activity relationships of the compounds were studied using molecular docking.