727993-34-2 Usage
Description
6-methoxy-2-(trifluoromethyl)pyridin-3-amine is a pyridine derivative with the molecular formula C8H7F3N2O. It features a methoxy group and a trifluoromethyl group attached to the pyridine ring, which endows it with unique chemical properties and potential applications in various fields.
Uses
Used in Organic Synthesis:
6-methoxy-2-(trifluoromethyl)pyridin-3-amine is utilized as a key intermediate in organic synthesis for the creation of complex organic molecules. Its presence of both electron-donating and electron-withdrawing groups allows for versatile reactivity and the formation of a wide range of compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-methoxy-2-(trifluoromethyl)pyridin-3-amine is employed as a building block for the synthesis of biologically active molecules. Its unique structure contributes to the development of new pharmaceutical agents with potential therapeutic benefits.
Used in Drug Development:
6-methoxy-2-(trifluoromethyl)pyridin-3-amine is used as a valuable tool in drug development. Researchers leverage its chemical properties to design and synthesize new drugs and therapeutic agents, aiming to address various medical conditions and improve patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 727993-34-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,7,9,9 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 727993-34:
(8*7)+(7*2)+(6*7)+(5*9)+(4*9)+(3*3)+(2*3)+(1*4)=212
212 % 10 = 2
So 727993-34-2 is a valid CAS Registry Number.
727993-34-2Relevant articles and documents
Therapeutically Active Thiazolo-Pyrimidine Derivatives
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Paragraph 0275; 0276; 0292, (2014/10/29)
A series of thiazolo[5,4-d]pyrimidine derivatives of formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: (I) Q represents a group of formula (Qa), (Qb), (Qc), (Qd) or (Qe) are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection.
COMPOUNDS AS CRF1 RECEPTOR ANTAGONISTS
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Page 27, (2010/02/09)
The present invention relates to compounds of Formula I,or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compounds of the inventions are CRF, receptor antagonists. Compounds of the invention are useful for t
CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine.
Arvanitis, Argyrios G,Arnold, Charles R,Fitzgerald, Lawrence W,Frietze, William E,Olson, Richard E,Gilligan, Paul J,Robertson, David W
, p. 289 - 291 (2007/10/03)
A series of imidazo[4,5-b]pyridines with a 7-(3-pyridyl) substituent is described as high affinity CRF receptor ligands. Individual analogues were synthesized from key intermediates obtained via palladium-catalyzed coupling of 3-pyridyl zinc or boronic acid organometallic intermediates with 2-benzyloxy-4-chloro-3-nitropyridine 12.
