72802-41-6

Basic information

• Product Name: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE
• Synonyms: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE;2-Hydroxy-1-(3-nitro-phenyl)-ethanone
• CAS NO: 72802-41-6
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 72802-41-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 88-90°C
• Boiling Point: 297°C at 760 mmHg
• Flash Point: 131.9°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 0.000624mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(72802-41-6)
• EPA Substance Registry System: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(72802-41-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 72802-41-6(Hazardous Substances Data)

Usage

General Description

2-Hydroxy-1-(3-nitrophenyl)-1-ethanone is a type of chemical compound that consists of both organic and inorganic substances. This particular chemical is characterized by its molecular structure containing a nitrophenyl group, an ethanone group, and a hydroxy group. The specific presence of these groups suggests that this compound exhibits characteristics typical of both ketones and phenyl groups. The nitro group in its structure likely gives it certain reactive properties, potentially contributing to its potential uses in various chemical and scientific applications. However, the specific uses, safety measures, and hazard characteristics of this chemical are not commonly detailed, indicating that it might not be broadly used or extensively studied. Therefore, it is important to treat this chemical with caution, understanding its reactivity and potential hazards before use.

InChI:InChI=1/C8H7NO4/c10-5-8(11)6-2-1-3-7(4-6)9(12)13/h1-4,10H,5H2

Upstream product

• 90945-65-6 2-acetoxy-1-(3-nitrophenyl)ethanone 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 92554-40-0 α-tosyloxy-m-nitroacetophenone 

Downstream Products

• 121-92-6 3-nitrobenzoic acid 
• 124-38-9 carbon dioxide 
• 287944-26-7 (S)-(+)-1-(3-nitrophenyl)-1,2-ethanediol 
• 76116-24-0 (R)-1-(3-nitrophenyl)ethanol 
• 899596-52-2 4-chlorobenzyl 3-nitrobenzoate 
• 108521-49-9 prop-2-yn-1-yl 3-nitrobenzoate 
• 15875-88-4 2-chloroethyl 3-nitrobenzoate 
• 27800-03-9 m-Nitrobenzoesaeure-β-bromethylester 
• 6268-25-3 n-butyl 3-nitrobenzoate 
• 1415049-18-1 1-(3-nitrophenyl)-2-(piperidin-1-yl)ethane-1,2-dione 

Relevant articles and documents

Regioselective three-component synthesis of 1,2-diarylindoles from cyclohexanones, α-hydroxyketones and anilines under transition-metal-free conditions

A facile method for the one-pot synthesis of 1,2-diarylindoles under transition-metal-free conditions is described. Cyclohexanones were used as the aryl sources via the dehydrogenative aromatization process. One C-C and two C-N bonds were selectively formed via a domino reaction. This protocol provides a convenient approach for the construction of valuable bioactive 1,2-diarylindoles from readily available cyclohexanones, α-hydroxyketones and anilines.

Microbial transformation of 2-hydroxy and 2-acetoxy ketones with Geotrichum sp.

Biotransformation of a series of o-, m- and p-substituted α-hydroxy- and α-acetoxyphenylethanones 1a-h and 9a-g with Geotrichum sp. led to the corresponding 1,2-diols 2 and/or monoacetates 10 in moderate to excellent enantiomeric excesses. α-Hydroxy- and α-acetoxyphenylethanones and their m- and p-derivatives gave preponderantly the S-configuration products while in the case of the o-derivatives R-alcohol was provided as the major enantiomer. The results of stereoselectivity were discussed. (C) 2000 Elsevier Science Ltd.