73-24-5Relevant articles and documents
Using conformationally locked nucleosides to calibrate the anomeric effect: Implications for glycosyl bond stability
Moon, Hyung Ryong,Siddiqui, Maqbool A.,Sun, Guangyu,Filippov, Igor V.,Landsman, Nicholas A.,Lee, Yi-Chien,Adams, Kristie M.,Barchi Jr., Joseph J.,Deschamps, Jeffrey R.,Nicklaus, Marc C.,Kelley, James A.,Marquez, Victor E.
, p. 6707 - 6717 (2010)
Steric and electronic parameters, such as the anomeric effect (AE) and gauche effect play significant roles in steering the North⇆South equilibrium of nucleosides in solution. Two isomeric oxa-bicyclo[3.1.0]hexane nucleosides that are conformational
Plasmonic Hot Electron-Mediated Hydrodehalogenation Kinetics on Nanostructured Ag Electrodes
Liu, Jia,Cai, Zhuan-Yun,Sun, Wei-Xin,Wang, Jia-Zheng,Shen, Xiao-Ru,Zhan, Chao,Devasenathipathy, Rajkumar,Zhou, Jian-Zhang,Wu, De-Yin,Mao, Bing-Wei,Tian, Zhong-Qun
supporting information, p. 17489 - 17498 (2020/11/12)
An attractive field of plasmon-mediated chemical reactions (PMCRs) is developing rapidly, but there is still incomplete understanding of how to control the kinetics of such a reaction related to hot carriers. Here, we chose 8-bromoadenine (8BrAd) as a probe molecule of hot electrons to investigate the influence of the electrode potential, laser wavelength, and power on the PMCR kinetics on silver nanoparticle-modified silver electrodes. Plasmonic hot electron-mediated cleavage of the C-Br bond in 8BrAd has been investigated by combining in situ electrochemical surface-enhanced Raman spectroscopy and density functional theory calculations. The experimental and theoretical results reveal that the energy position of plasmon relaxation-generated hot electrons can be modulated conveniently by applied potentials and laser light. This allows the proposal of a mechanism of modulating the matching energy of the hot electron of plasmon relaxation to promote the efficiency of PMCRs in electrochemical interfaces. Our work will be helpful to design surface plasmon resonance photoelectrochemical reactions on metal electrode surfaces of nanostructures with higher efficiency.
Adenine intermediate pyrimidine-azo compound and preparation method thereof
-
Paragraph 0023, (2017/07/14)
The invention relates to an adenine intermediate pyrimidine-azo compound and a preparation method thereof. The preparation method comprises the following steps of: 1) dissolving primary amine in mixed-acid solution, dripping sodium nitrite solution to prepare diazonium salt shown in a formula (3), adding malononitrile for dissolving, and dripping alkaline solution to regulate a pH value of reaction solution and generate coupling reaction, thereby obtaining an intermediate pyrimidine-azo compound (4); 2) adding the intermediate pyrimidine-azo compound (4) prepared in the step 1) into formamide, introducing liquid ammonia, and heating to carry out high-temperature condensation and cyclization reaction, thereby obtaining an adenine intermediate pyrimidine-azo compound (5), wherein a series of derivatives of the adenine intermediate pyrimidine-azo compound can be prepared by selecting different primary amines. The adenine intermediate pyrimidine-azo compound and the preparation method have the advantages that water is used as a solvent in the step 1), and the solvent used in the step 2) can be repeatedly used, so that the 'three wastes' are fewer, and the environment-friendly effect is achieved; and the cost is low, so that the industrialization is easy and the economic benefit is obvious.
Biosynthesis of 4-aminoheptose 2-epimers, core structural components of the septacidins and spicamycins
Price, Neil P.J.,Furukawa, Takayuki,Cheng, Fang,Qi, Jianzhao,Chen, Wenqing,Crich, David
, p. 405 - 414 (2014/06/10)
Septacidins and spicamycins are acylated 4-aminoheptosyl-β-N- glycosides produced by Streptomyces fimbriatus and S. alanosinicus, respectively. Their structures are highly conserved, but differ in the stereochemistry of the 4-aminoheptosyl residues. The o