7303-50-6

Basic information

• Product Name: 7-AZATRYPTOPHAN
• Synonyms: DL-7-AZATRYPTOPHANE extrapure;7-Aza-DL-tryptophan;1H-Pyrrolo[2,3-b]pyridine-3-alanine;Aza-T;NSC 19495;DL-7-Azatryptophan hydrochloride;2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid, 3-(2-Amino-2-carboxyethyl)-1H-pyrrolo[2,3-b]pyridine;1H-pyrrolo[2,3-b]pyridine (R)-2-aminopropanoate
• CAS NO: 7303-50-6
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.21
• Product Categories: Fluorescent Labels & Indicators;A - H;Amino Acids;Modified Amino Acids;Indole Derivatives;amino;Amino Acids 13C, 2H, 15N;Peptide;Amino Acids & Derivatives
• Mol File: 7303-50-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 275°C dec.
• Boiling Point: 466.1 °C at 760 mmHg
• Flash Point: 235.7 °C
• Appearance: Slightly off-white/Crystalline Powder
• Density: 1.434 g/cm³
• Storage Temp.: −20°C
• PKA: 2.20±0.10(Predicted)
• CAS DataBase Reference: 7-AZATRYPTOPHAN(CAS DataBase Reference)
• NIST Chemistry Reference: 7-AZATRYPTOPHAN(7303-50-6)
• EPA Substance Registry System: 7-AZATRYPTOPHAN(7303-50-6)

Safety Data

• WGK Germany: 3
• RTECS: UY8810000
• Hazardous Substances Data: 7303-50-6(Hazardous Substances Data)

Usage

Chemical Properties

White Powder

Uses

DL-7-Azatryptophan is an unusual alpha-amino acid with a very potent fluorescent activity. Its used as a vehicle for probing the structure and dynamics of protein and peptides

InChI:InChI=1/C10H11N3O2/c11-8(10(14)15)4-6-5-13-9-7(6)2-1-3-12-9/h1-3,5,8H,4,11H2,(H,12,13)(H,14,15)

Upstream product

• 211179-97-4 diethyl 2-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-2-acetamidomalonate 
• 5654-92-2 7-azagramine 
• 271-63-6 7-Azaindole 
• 87358-28-9 N,N,N-trimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanaminium iodide 

Downstream Products

• 4649-12-1 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-ethylamine 
• 1295647-38-9 (5aR,10R)-10-benzo[1,3]dioxol-5-yl-7-[(R)-1-benzylpyrrolidin-3-yl]-5,5a,7,8,10,11-hexahydro-1,7,9a,11-tetraaza-benzo[b]fluorene-6,9-dione 
• 737007-45-3 C₂₅H₂₁N₃O₄ 
• 134235-82-8 (-)-(R)-7-azatryptophan 
• 49758-35-2 (S)-2-amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid 

Relevant articles and documents

MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80 (B7-1)/PD-LI PROTEIN/PROTEIN INTERACTIONS

The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.