7309-55-9

Basic information

• Product Name: (2S,3S)-N-benzoyl-3-phenylisoserine
• Synonyms: (2S,3S)-N-benzoyl-3-phenylisoserine
• CAS NO: 7309-55-9
• Molecular Weight: 285.299
• Mol File: 7309-55-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (2S,3S)-N-benzoyl-3-phenylisoserine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-N-benzoyl-3-phenylisoserine(7309-55-9)
• EPA Substance Registry System: (2S,3S)-N-benzoyl-3-phenylisoserine(7309-55-9)

Safety Data

• Hazardous Substances Data: 7309-55-9(Hazardous Substances Data)

Upstream product

• 32981-85-4 syn-(+/-)-2-hydroxy-3-(benzoylamino)-3-phenylpropanoic acid methyl ester 
• 7309-53-7 threo-3-phenylisoserine 
• 98-88-4 benzoyl chloride 
• 19190-80-8 methyl trans-3-phenylglycidate 
• 146848-89-7 (2S,3S)-(+)-isobutyl 3-azido-2-benzoxy-3-phenylpropionate 
• 146848-88-6 (2S,3S)-(+)-isobutyl 3-azido-2-hydroxy-3-phenylpropionate 
• 146848-87-5 (+)-isobutyl (2S,3R)-3-phenylglycidate 
• 17599-61-0 N-benzylidene-1,1,1-trimethylsilanamine 
• 195196-19-1 C₄₁H₆₁NO₄Si₂ 
• 195196-15-7 (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone 
• 100-52-7 benzaldehyde 
• 127001-34-7 N-Benzylidene<(R)-(-)-α-methylbenzyl>amine N-oxide 
• 181294-27-9 (2S,3S)-3-Benzoylamino-2-hydroxy-3-phenyl-thiopropionic acid S-phenyl ester 
• 180718-63-2 (+)-(4S,5S)-3-benzoyl-4-phenyloxazolidin-2-one-5-carboxylic acid 

Downstream Products

• 32981-85-4 syn-(+/-)-2-hydroxy-3-(benzoylamino)-3-phenylpropanoic acid methyl ester 
• 146848-91-1 (4S,5R)-2,4-diphenyl-2-oxazoline-5-carboxylic acid methyl ester 
• 132201-33-3 (2R,3S)-N-benzoyl-3-phenylisoserine 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 144541-45-7 methyl (2S,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 

Relevant articles and documents

A convenient one-pot approach to Paclitaxel (Taxol) side chain via 1,3-dipolar cycloaddition of carbonyl ylides and N-benzoylbenzyl imines

An efficient cascade approach to α-hydroxy-β-amino acid derivatives is reported, which goes through a 1,3-dipolar cycloaddition of carbonyl ylides and N-benzoylbenzyl imines and followed by hydrolysis under acidic conditions. This is the first example of using N-benzoylbenzyl imine as dipolarophile for 1,3-dipolar cycloaddition with carbonyl ylide, which provides a direct and convenient access for the one-pot synthesis of paclitaxel side chain and its derivatives.

A practical and stereoselective synthesis of taxol side chain

Apractical and efficient synthesis of taxol C-13 side chain from cheap and easily available starting material is described.

Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes

Reduction and resolution methods for the preparation of compounds useful as intermediates in the preparation of taxanes, and particularly for preparation of desired stereoisomers for use in the formation of the C-13 sidechain of pharmaceutically useful taxanes such as paclitaxel.