731-00-0

Basic information

• Product Name: 4,4,4-TRIFLUORO-3-HYDROXY-3-(TRIFLUOROMETHYL)BUTYROPHENONE, 97% MIN.
• Synonyms: 4,4,4-TRIFLUORO-3-HYDROXY-3-(TRIFLUOROMETHYL)BUTYROPHENONE, 97% MIN.;3-Hydroxy-1-phenyl-4,4,4-trifluoro-3-(trifluoromethyl)butan-1-one;3-Hydroxy-4,4,4-trifluoro-3-(trifluoromethyl)butyrophenone, 2-[Benzoyl(methyl)]-1,1,1,3,3,3-hexafluoropropan-2-ol;3-Hydroxy-4,4,4-trifluoro-3-(trifluoromethyl)butyrophenone, 2-(2-Oxo-2-phenylethyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
• CAS NO: 731-00-0
• Molecular Formula: C₁₁H₈F₆O₂
• Molecular Weight: 286.17
• Mol File: 731-00-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 311.3°C at 760 mmHg
• Flash Point: 142.1°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 0.000244mmHg at 25°C
• Refractive Index: 1.436
• PKA: 8.95±0.29(Predicted)
• CAS DataBase Reference: 4,4,4-TRIFLUORO-3-HYDROXY-3-(TRIFLUOROMETHYL)BUTYROPHENONE, 97% MIN.(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-TRIFLUORO-3-HYDROXY-3-(TRIFLUOROMETHYL)BUTYROPHENONE, 97% MIN.(731-00-0)
• EPA Substance Registry System: 4,4,4-TRIFLUORO-3-HYDROXY-3-(TRIFLUOROMETHYL)BUTYROPHENONE, 97% MIN.(731-00-0)

Safety Data

• Hazardous Substances Data: 731-00-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H8F6O2/c12-10(13,14)9(19,11(15,16)17)6-8(18)7-4-2-1-3-5-7/h1-5,19H,6H2

Upstream product

• 4577-41-7 1,1,1-trifluoro-4-phenyl-2-(trifluoromethyl)but-3-yn-2-ol 
• 143211-22-7 4,4,4-Trifluoro-1-phenyl-3-trifluoromethyl-3-trimethylsilanyloxy-butan-1-one 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 684-16-2 Hexafluoroacetone 
• 7196-01-2 4-(1-phenylvinyl)morpholine 
• 98-86-2 acetophenone 
• 6738-06-3 phenylethynylmagnesium bromide 

Downstream Products

• 35443-84-6 4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one 
• 923018-85-3 1-cyclohexyl-4,4,4-trifluoro-3-(trifluoromethyl)butane-l,3-diol 
• 34844-51-4 1-phenyl-4,4,4-trifluoro-3-(trifluoromethyl)butane-l,3-diol 

Relevant articles and documents

Efficient and convenient entry to β-hydroxy-β-trifluoromethyl-β-substituted ketones and 2,6-disubstituted 4-trifluoromethylpyridines based on the reaction of trifluoromethyl ketones with enamines or imines

The reactions of trifluoromethyl ketones with enamines or imines are described. The reaction of trifluoroacetone with enamines or imines followed by hydrolysis gave the corresponding β-hydroxyβ-trifluoromethyl-β-methyl ketones in good yields. The reaction

Fluorinated alkoxy-imino catalyst components

This invention relates to fluorinated alkoxy-imino metallic complexes and their use in catalyst systems for the polymerisation or oligomerisation of ethylene and alpha-olefins.

The cross-aldol reaction of hexafluoroacetone (HFA) with ketones catalyzed by an acid

The cross-aldol reactions of hexafluoroacetone (HFA) and ketones using an acid catalyst are reported. When concentrated sulfuric acid was employed as the catalyst, HFA reacted regioselectively with various ketones at 50-100 °C to give the aldol adducts (6) in good yields. The reaction is initiated by an acid-catalyzed transformation of the ketone into the corresponding enol that reacts with HFA. The obtained adducts (6) can be reduced with hydrogen under a Ru/C catalyst to lead to the corresponding fluorine-containing diols (13).