35443-84-6Relevant articles and documents
Cobalt-Catalyzed Hydroxyperfluoroalkylation of Alkenes with Perfluoroalkyl Bromides and Atmospheric Oxygen
Sun, Qilin,Pang, Liangzhi,Mao, Shuxian,Fan, Wu,Zhou, Yuyi,Xu, Jing,Li, Suhua,Li, Qiankun
, p. 1353 - 1364 (2021/12/02)
A mild and efficient method for the cobalt-catalyzed hydroxyperfluoroalkylation of alkenes has been developed. This method demonstrated broad substrate scope, good yields, and mild conditions with the tolerance of mono-, di-, and trisubstituted alkenes including both styrenes and non-activated aliphatic olefins. This strategy offered a valuable solution for rapid and efficient construction of β-perfluoroalkyl alcohols using widely available and inexpensive perfluoroalkyl bromides and atmospheric oxygen.
REGIOSPECIFIC α-HEXAFLUOROISOPROPYLIDENATION OF KETONES USING HEXAFLUOROACETONE
Ishihara, Takashi,Shinjo, Hiroshi,Inoue, Yoshihisa,Ando, Teiichi
, p. 1 - 20 (2007/10/02)
Hexafluoroacetone (HFA) reacted regiospecifically with various enol silyl ethers at -30 to -35 deg C in the presence of a Lewis acid to give HFA aldols, or α-bis(trifluoromethyl)hydroxymethyl carbonyl compounds, in good yields.The reaction of HFA with die