140860-85-1Relevant articles and documents
Partially fluorinated heterocycles from 4,4-bis(trifluoromethyl)-hetero-1, 3-dienes via C-F bond activation - Synthesis of 2-fluoro-3-(trifluoromethyl) furans
Burger, Klaus,Helmreich, Brigitte,Hennig, Lothar,Spengler, Jan,Albericio, Fernando,Fuchs, Annett
, p. 227 - 236 (2008/02/01)
An efficient synthesis of 2-fluoro-3-(trifluoromethyl)furans was developed. Keystep of the reaction sequence is a [4 + 1] cycloaddition reaction of tin(II)chloride to 4,4-bis(trifluoromethyl)-1-oxabuta-1,3-dienes. At elevated temperatures the tin heterocy