143541-34-8

Basic information

• Product Name: Furan, 2,5-diphenyl-3-(trifluoromethyl)-
• CAS NO: 143541-34-8
• Molecular Formula: C17H11F3O
• Molecular Weight: 288.269
• Mol File: 143541-34-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Furan, 2,5-diphenyl-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, 2,5-diphenyl-3-(trifluoromethyl)-(143541-34-8)
• EPA Substance Registry System: Furan, 2,5-diphenyl-3-(trifluoromethyl)-(143541-34-8)

Safety Data

• Hazardous Substances Data: 143541-34-8(Hazardous Substances Data)

Upstream product

• 140860-79-3 4,4-difluoro-1-phenyl-3-(trifluoromethyl)but-3-en-1-one 
• 114192-88-0 (E)-4,4,4-trifluoro-1-phenylbut-2-en-1-one 
• 98-88-4 benzoyl chloride 
• 35443-84-6 4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one 
• 591-51-5 phenyllithium 
• 140860-85-1 2-fluoro-5-phenyl-3-(trifluoromethyl)furan 

Relevant articles and documents

Transition-Metal-Free Synthesis of Trifluoromethylated Furans via a Bu3P-Mediated Tandem Acylation-Wittig Reaction

A highly efficient nucleophilic addition- O -acylation-intramolecular Wittig reaction of β-trifluoromethyl α,β-enones is disclosed. This strategy features mild reaction conditions and provides a practical transition-metal-free method to a set of biologically significant trifluoromethylated furans in high yields with diverse functional groups.

Ein neues Verfahren zur positionsselektiven Einfuehrung von Trifluormethylgruppen in Heteroaromaten: Synthese von 3-Trifluormethylfuranen

Transformation of 4,4-bis(trifluoromethyl)-1-oxabuta-1,3-dienes (2) into 2-fluoro-3-trifluoromethylfurans (4) can be achieved in a two step procedure by treatment with tin(II) chloride and sodium hydride.The fluorine atom at skeleton position 2 is replace