73258-94-3

Basic information

• Product Name: Benzamide, 2,4-dimethyl- (9CI)
• Synonyms: Benzamide, 2,4-dimethyl- (9CI);2,4-DIMETHYLBENZAMIDE
• CAS NO: 73258-94-3
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Product Categories: AMIDE
• Mol File: 73258-94-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzamide, 2,4-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2,4-dimethyl- (9CI)(73258-94-3)
• EPA Substance Registry System: Benzamide, 2,4-dimethyl- (9CI)(73258-94-3)

Safety Data

• Hazardous Substances Data: 73258-94-3(Hazardous Substances Data)

Upstream product

• 21789-36-6 2,4-dimethylbenzonitrile 
• 463-72-9 carbamic chloride 
• 108-38-3 m-xylene 
• 33108-92-8 (2,4-dimethyl-phenyl)-glyoxylonitrile 
• 51-79-6 urethane 
• 7664-93-9 sulfuric acid 
• 1140-14-3 2,4-Dimethyl benzophenone 
• 71-43-2 benzene 
• 21900-42-5 2,4-dimethylbenzoyl chloride 
• 611-01-8 2,4-dimethyl-benzoic acid 
• 89-74-7 2,4-dimethylacetophenone. 
• 2234-20-0 2,4-dimethylstyrene 
• 15764-16-6 2,4-dimethylbenzaldehyde 
• 64-18-6 formic acid 

Downstream Products

• 611-01-8 2,4-dimethyl-benzoic acid 
• 57182-70-4 2,4-Dimethylthiobenzamid 

Relevant articles and documents

Supported palladium catalyzed aminocarbonylation of aryl iodides employing bench-stable CO and NH3surrogates

A simple, efficient and phosphine free protocol for carbonylative synthesis of primary aromatic amides under polystyrene supported palladium (Pd?PS) nanoparticle (NP) catalyzed conditions has been demonstrated. Herein, instead of using two toxic and difficult to handle gases simultaneously, we have employed the solid, economical, bench stable oxalic acid as the CO source and ammonium carbamate as the NH3source in a single pot reaction. For the first time, we have applied two non-gaseous surrogates simultaneously under heterogeneous catalyst (Pd?PS) conditions for the synthesis of primary amides using an easy to handle double-vial (DV) system. The developed strategy showed a good functional group tolerance towards a wide range of aryl iodides and afforded primary aromatic amides in good yields. The Pd?PS catalyst was easy to separate and can be recycled up to four consecutive runs with small loss in catalytic activity. We have successfully extended the scope of the methodology to the synthesis of isoindole-1,3-diones from 1,2-dihalobenzene, 2-halobenzoates and 2-halobenzoic acid following double and single carbonylative cyclization approaches.

A Convenient Palladium-Catalyzed Aminocarbonylation of Aryl Iodides to Primary Amides under Gas-Free Conditions

A convenient procedure for the synthesis of aromatic primary amides through palladium-catalyzed aminocarbonylation of aryl iodides has been developed. With ammonium hydrogen carbonate as the solid nitrogen source and formic acid as the liquid CO source, a variety of primary amides were obtained in moderate to excellent yields under gas-free conditions.

A novel oxidative procedure for the synthesis of benzamides from styrenes and amines under metal-free conditions

An interesting procedure for the oxidative synthesis of amides from styrenes and amines has been developed. Various primary amides were formed in moderate yields (25-81%). Secondary amides can be produced in moderate yields as well (41-68%). Notably, no transition metal catalyst was needed for this transformation. This is the first example of oxidative transformation of styrenes to benzamides. This journal is the Partner Organisations 2014.