73611-78-6

Basic information

• Product Name: (Z)-(4-bromobut-1-en-1-yl)benzene
• Synonyms: (Z)-(4-bromobut-1-en-1-yl)benzene
• CAS NO: 73611-78-6
• Molecular Weight: 211.101
• Mol File: 73611-78-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (Z)-(4-bromobut-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(4-bromobut-1-en-1-yl)benzene(73611-78-6)
• EPA Substance Registry System: (Z)-(4-bromobut-1-en-1-yl)benzene(73611-78-6)

Safety Data

• Hazardous Substances Data: 73611-78-6(Hazardous Substances Data)

Upstream product

• 1007-03-0 1-phenyl-1-cyclopropylmethanol 
• 20047-19-2 (Z)-4-phenylbut-3-en-1-ol 
• 100-58-3 phenylmagnesium bromide 
• 23459-38-3 1-phenylcyclopropylmethylamine 
• 106-93-4 ethylene dibromide 
• 536-74-3 phenylacetylene 
• 10229-11-5 4-phenyl-but-3-yn-1-ol 
• 5162-44-7 1-bromo-4-butene 
• 108-90-7 chlorobenzene 
• 100-52-7 benzaldehyde 
• 770-36-5 4-phenylbuta-3-en-1-ol 
• 79135-06-1 (Cyclopropylphenylmethoxy)magnesium bromide 

Downstream Products

• 1330074-82-2 C₁₉H₁₆ClNO 
• 27066-35-9 (E)-1,4-diphenylbut-1-ene 
• 7302-00-3 (E)-1,3-diphenyl-1-butene 
• 13633-25-5 1-Bromo-4-phenylbutane 
• 147429-91-2 1-Methyl-4-((Z)-4-phenyl-but-3-enyl)-piperazine 
• 1352632-27-9 C₁₉H₁₆ClNO 
• 1352632-28-0 C₂₀H₁₈ClNO 
• 824-90-8 1-phenylbut-1-ene 

Relevant articles and documents

Ground-State Electron Transfer as an Initiation Mechanism for Biocatalytic C-C Bond Forming Reactions

The development of non-natural reaction mechanisms is an attractive strategy for expanding the synthetic capabilities of substrate promiscuous enzymes. Here, we report an "ene"-reductase catalyzed asymmetric hydroalkylation of olefins using α-bromoketones as radical precursors. Radical initiation occurs via ground-state electron transfer from the flavin cofactor located within the enzyme active site, an underrepresented mechanism in flavin biocatalysis. Four rounds of site saturation mutagenesis were used to access a variant of the "ene"-reductase nicotinamide-dependent cyclohexanone reductase (NCR) from Zymomonas mobiles capable of catalyzing a cyclization to furnish β-chiral cyclopentanones with high levels of enantioselectivity. Additionally, wild-type NCR can catalyze intermolecular couplings with precise stereochemical control over the radical termination step. This report highlights the utility for ground-state electron transfers to enable non-natural biocatalytic C-C bond forming reactions.

Preparation method for p-phenylbutoxybenzoic acid

The invention provides a preparation method for p-phenylbutoxybenzoic acid, belonging to the field of organic synthesis. According to the invention, palladium-based catalytic coupling is adopted, andthe Grignard reaction and the Friedel-Craft reaction are avoided, thereby avoiding the production of blue-green copper ion wastewater and generation of a large amount of acidic wastewater due to usageof aluminum trichloride; the preparation method of the invention is friendly to environment, simple in synthesis route and high in the yield of each step; and halogeno-benzene is used for replacing more expensive phenylmagnesium bromide and used as a starting material, so the preparation cost of p-phenylbutoxybenzoic acid is lowered. The p-phenylbutoxybenzoic acid obtained in the invention has good crystal form, high purity and good solubility. The data of embodiments of the invention show that the total yield of p-phenylbutoxybenzoic acid prepared in the invention is 60% or above, and the HPLC purity of p-phenylbutoxybenzoic acid is 99.9% or above.

One-pot synthesis of benzo[f]quinolin-3-ones and benzo[a]phenanthridein-5- ones by the photoanuulation of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1- ones to phenylacetylene

The one-pot synthesis of benzo[f]quinolin-3-ones and benzo[a] phenanthridein-5-ones was achieved by the inter- and intramolecular photoannulation of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1-ones with phenylacetylene or tethered phenylacetylene. The reactions were proceeded by photoaddition of 6-chloropyridin-2-ones and 3-chloroisoquinolin-1-ones to phenylacetylene to give the chlorine-substituted stilbenoids, and then 6π electrocyclization of the stilbenoids and oxidation aromatization to afford the polycyclic products.