770-36-5

Basic information

• Product Name: 3-Buten-1-ol, 4-phenyl-, (3E)-
• CAS NO: 770-36-5
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Mol File: 770-36-5.mol
• Article Data: 94

Chemical Properties

• CAS DataBase Reference: 3-Buten-1-ol, 4-phenyl-, (3E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-1-ol, 4-phenyl-, (3E)-(770-36-5)
• EPA Substance Registry System: 3-Buten-1-ol, 4-phenyl-, (3E)-(770-36-5)

Safety Data

• Hazardous Substances Data: 770-36-5(Hazardous Substances Data)

Upstream product

• 2243-53-0 styrylacetic acid 
• 14580-93-9 2,2,2-Triphenyl-1,2-λ⁵-oxaphospholan 
• 100-52-7 benzaldehyde 
• 54674-84-9 γ-hydroxypropyltriphenylphosphonium chloride 
• 53045-69-5 3-chloro-2-phenyl-tetrahydro-furan 
• 60-29-7 diethyl ether 
• 28525-69-1 (4E)-5-phenyl-4-pentenoic acid 
• 110-86-1 pyridine 
• 67-56-1 methanol 
• 51860-45-8 3-hydroxypropyltriphenylphosphonium bromide 
• 5629-57-2 ethyl cinnamate 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 3481-02-5 cyclopropyl phenyl ketone 
• 1205-84-1 ethyl (E)-4-phenylbut-3-enoate 

Downstream Products

• 16133-83-8 tetrahydro-2-phenylfuran 
• 77722-63-5 4-nitro-benzoic acid-(4-phenyl-but-3-enyl ester) 
• 1025966-70-4 C₁₁H₁₁ClO₂ 
• 99376-56-4 4-phenyl-3-buten-1-yl 3,3-dimethyl-2-phenylcyclopropenecarboxylate 
• 105632-42-6 4-Phenyl-3,4-epoxy-1-butanol 
• 145576-38-1 (E)-4-phenylbut-3-en-1-yl 2-diazoacetate 
• 7515-41-5 (E)-(4-bromobut-1-en-1-yl)benzene 
• 127083-17-4 C₁₀H₁₁⁽²⁾HO 
• 40283-22-5 Phosphoric acid 2,2-dichloro-vinyl ester (E)-4-phenyl-but-3-enyl ester (Z)-4-phenyl-but-3-enyl ester 
• 40283-23-6 Phosphoric acid 2,2-dichloro-vinyl ester bis-((E)-4-phenyl-but-3-enyl) ester 
• 40283-15-6 Phosphoric acid 2,2-dichloro-vinyl ester methyl ester (E)-4-phenyl-but-3-enyl ester 
• 2134-29-4 3-Hydroxypropanal 
• 16133-83-8 (S)-2-phenyltetrahydrofuran 

Relevant articles and documents

Palladium-Catalyzed Tandem Hydrocarbonylative Lactamization and Cycloaddition Reaction for the Construction of Bridged Polycyclic Lactams

The intramolecular hydroaminocarbonylation of alkenes is a compelling tool to rapidly access lactam, a privileged motif ubiquitous in natural products, pharmaceuticals, and agrochemicals. However, selective carbonylation to bridged polycyclic lactams with a lactam nitrogen at a bridgehead position is less explored. We herein report a modular palladium-catalyzed approach to perform a tandem hydrocarbonylative lactamization/Diels-Alder cycloaddition reaction with 2-vinyl aryl aldimines, alkenes, and CO, which offers convenient access to furnish the bridged polycyclic lactams in high yields with high selectivities.

Are bis(pyridine)iodine(i) complexes applicable for asymmetric halogenation?

Enantiopure halogenated molecules are of tremendous importance as synthetic intermediates in the construction of pharmaceuticals, fragrances, flavours, natural products, pesticides, and functional materials. Enantioselective halofunctionalizations remain

Nickel-Catalyzed 1,2-Carboamination of Alkenyl Alcohols

An alcohol-directed, nickel-catalyzed three-component umpolung carboamination of unactivated alkenes with aryl/alkenylboronic esters and electrophilic aminating reagents is reported. This transformation is enabled by specifically tailored O-(2,6-dimethoxybenzoyl)hydroxylamine electrophiles that suppress competitive processes, including undesired β-hydride elimination and transesterification between the alcohol substrate and electrophile. The reaction delivers the desired 1,2-carboaminated products with generally high regio- and syn-diastereoselectivity and exhibits a broad scope of coupling partners and alkenes, including complex natural products. Various mechanistic experiments and analysis of the stereochemical outcome with a cyclic alkene substrate, as confirmed by X-ray crystallographic analysis, support alcohol-directed syn-insertion of an organonickel(I) species.